UP mathematicians find safer contraceptive hormone doses

UP mathematicians find safer contraceptive hormone doses

Published: May 9, 2023

By: Eunice Jean C. Patron

The amount of hormones in contraceptives can be reduced by as much as 92% without impacting their effectiveness, new math research from the University of the Philippines – Diliman College of Science (UPD-CS) has found.

Using mathematical models, researchers from the UPD-CS institute of Mathematics have found that contraceptives can still remain effective despite reducing their hormone content by as much as 92%. (Photo credit: Towfiqu Barbhuiya / Pexels.com)

Most contraceptives available today contain either or both estrogen and progesterone hormones to block ovulation, the phase of the menstrual cycle wherein an egg is released into the uterus. But while effective, hormonal contraception has its drawbacks: an increased potential for blood clots, heart attacks, strokes, mood disorders, and other health risks.

 

UPD-CS Institute of Mathematics (UPD-CS IM) Ph.D. Mathematics graduate Brenda Lyn Gavina and Associate Professor Dr. Aurelio de los Reyes V, alongside collaborators Dr. Mette Olufsen of North Carolina State University, Dr. Suzanne Lenhart of the University of Tennessee, and Dr. Johnny Ottesen of the Roskilde University of Denmark, analyzed the hormone levels of 23 women aged 20 to 34 years old with regular menstrual cycles. Their research revealed that estrogen-only contraceptives could work just as effectively even if hormone doses were reduced by as much as 92%. Meanwhile, hormone doses in progesterone-only contraceptives could be decreased by as much as 43% while still achieving the same effectivity.

 

In their study, the researchers developed a modified menstrual cycle model to track natural hormone levels and the effect of hormones taken through contraceptives. They then applied mathematics to determine the lowest amount of hormones needed to prevent ovulation. Apart from finding lower yet effective hormone dosages, they also found that intaking these contraceptives before the tenth day of the menstrual cycle is just as effective in preventing pregnancy as a daily dose.

 

The study opens new avenues for further research in hormonal birth control. “With the rapid development of new implants and injections providing continuous administration, there is great potential to implement new treatment scheme minimizing dose,” the researchers concluded in their study, published last April 13 in the journal PLoS Computational Biology.

 

“Reducing the dosage of hormonal contraceptives has been a longstanding objective of safer contraception. Our modeling/computational study suggests an effective and cost-efficient hormonal contraceptive administration.” Dr. de los Reyes said. “We also hope to build on the current model to investigate reproductive health concerns in women like polycystic ovarian syndrome (PCOS) and ovarian cysts. We would like to caution that our model is not directly translatable to clinical setup (or actual patients) as of yet, but the principles and its proof of concept could be potentially implemented to achieve safe and cost-efficient contraception.”

 

Researchers from the UP Diliman College of Science’s Institute of Mathematics, working alongside international colleagues, have found that the hormone levels in contraceptives could be cut by as much as 92% without impacting their effectiveness. (Photo credit: Aurelio de los Reyes V et al.)

For interview requests and other concerns, please contact media@science.upd.edu.ph

 

References:

Gavina, B. L. A., de los Reyes, A. A., Olufsen, M. S., Lenhart, S., & Ottesen, J. T. (2023). Toward an optimal contraception dosing strategy. PLOS Computational Biology, 19(4). https://doi.org/10.1371/journal.pcbi.1010073  

UP embarks on pioneering study into ‘Rugby’ abuse

UP embarks on pioneering study into ‘Rugby’ abuse

Published: April 28, 2023

By: Timothy James M. Dimacali

Scientists from across the University of the Philippines (UP) are pioneering a first-of-its-kind multidisciplinary study into the chemical, physical, and psychological impacts of solvent abuse on the country’s thousands of so-called “Rugby boys and girls.”

One of the research questions that UP scientists are trying to answer is if and how social behaviors in animals are affected by addiction to toluene, the key ingredient in “Rugby” contact cement. The researchers will then look at translating these findings to humans. (PHOTO CREDIT: Dr. Rohani Cena-Navarro)

Novel Approaches to Treatment of Addiction and Depression using Animal Models is a three-year research program spearheaded by the UP Manila National Institutes of Health (UPM-NIH), the National Center for Mental Health, the UP College of Medicine, the UP Philippine General Hospital, and the UP Diliman College of Science Institute of Chemistry (UPD-CS IC). It is being supervised by internationally-renowned neurobehavioral scientist Dr. Gregory Quirk of the University of Puerto Rico School of Medicine. 


“Attempts to treat toluene or ‘Rugby’ addiction have been largely unsuccessful due to severe withdrawal and craving symptoms that trigger relapse. What is needed to help adolescents overcome their addictions are new treatments that reduce toluene withdrawal and craving,” said program leader Dr. Rohani Cena-Navarro of the UPM-NIH.


“Rodent models have been used to develop such pharmacological treatments for other addictive drugs, but no such model has been developed for toluene. This collaboration between scientists and clinicians hopes to address this societal problem using laboratory animals,” she added.


This research is being  supported by the Department of Science and Technology – Philippine Council for Health Research and Development (DOST-PCHRD).


Origins of the nation’s thousands of ‘Rugby boys and girls’


The densely-populated urban streets of the Philippines are home and playground to as many as one million street children, many of whom are adolescents from the poorest families or even abandoned by parents. Left to fend for themselves, many turn to substance abuse to alleviate their hunger by inhaling toluene—an aromatic hydrocarbon solvent found in cheap and easily-obtainable contact cement, popularly sold under the “Rugby” brand name in local hardware stores. 


Estimated to number in the thousands nationwide, these young people eventually develop a physiological addiction and resort to begging, scavenging, or stealing not only to quell their hunger but also to sustain their toluene addiction.  Seeing groups of young boys—and girls!—running around the streets sniffing bags of glue has become so commonplace to the ordinary Filipino citizen, that the colloquial term “Rugby boys” is now a widely-used pejorative.


Substance abuse among street children is a long-standing societal issue that requires proper public health intervention. Acknowledging the need for local research to tackle inhalant abuse among adolescents will be very significant in providing recommendations and strengthening ongoing support systems, policies, and interventions. 


Addressing social issues and sex differences


So where does science fit into this societal issue? This is exactly what this team of researchers hopes to achieve by developing the first Addiction Research Laboratory in the country, using animal models.  


“In the years to come, it is our hope that the establishment of this Addiction Research Program will further open opportunities for research addressing the craving and withdrawal stages of addiction,” said UPD-CS IC’s Dr. Grace Gregorio, who is researching how toluene affects rats in an effort to understand the solvent’s effects on people. 


She and her fellow researchers are also looking into sex differences in the effects of toluene exposure, which represents a novel approach that has never been done before. “I bring in my analytical chemistry expertise to this meaningful undertaking by measuring toluene levels in the blood of male and female rodents,” Dr. Gregorio said. 


“There is much that we, as a society, don’t know and understand about solvent abuse. One of our research specialists, Jariel Bacar, rightly points out that girls can be affected too—and in very different ways from boys. The project is looking into what these differences are,” she explained. 


Developing tailored treatments for solvent-addicted adolescents


The first-ever model of its kind for toluene-based solvent addiction in the Philippines, this research is paving the way for new treatments for overcoming withdrawal and craving. The team hopes to translate their findings for use in human subjects as an attempt in addressing the pervasive drug addiction and chronic relapse in individuals.  Such experimental treatments for toluene have not been deeply investigated anywhere else in the world, because inhalant abuse is not as rampant in more developed countries. 


Now in its second year, the project has already completed its first two phases: identifying validated methods to quantify toluene in rodent blood and establishing the long-term effects of toluene after chronic exposure. Using validated methods, the team is investigating the effects of chronic exposure that last long after the drug has been stopped.  These include increased craving for the drug, increased anxiety, and impaired social functioning, all of which increase the likelihood of relapse following treatment. Novel treatments will be tested to diminish these withdrawal symptoms and restore the brain to its pre-addiction state.  


Ultimately, Novel Approaches to Treatment of Addiction and Depression using Animal Models aims to address one of the greatest challenges faced by today’s researchers: interweaving science into the fabric of a complex, busy, and highly diverse society to serve its well-intended purpose to the community that needs it the most. By the end of the project, the researchers hope to have developed tailored treatments for boys and girls who are addicted to toluene. 

The research team behind the multidisciplinary research program, Novel Approaches to Treatment of Addiction and Depression using Animal Models. Top row (L-R): Ajina Carampel (MD-PhD Student), Richelle Manalo, Dr. Grace Gregorio (UPD-CS IC), Dr. Rohani C. Navarro (Program Leader), Dr. Gregory Quirk (Supervising Scientist), Jariel Bacar and Johanna Munar (Project Technical Specialists I). Bottom row (L-R): Joannes Luke Asis (MD-PhD Student), Noel Agrava (Lab Aide), Brett Castro (University Research Associate), Dr. Bryan Bulatao (Project Leader), Herbert Montalban (Lab Aide), and Arturo Bermejo III (Project Assistant). (PHOTO CREDIT: Ilona Janairo)

For interview requests and more information on the multidisciplinary research program, Novel Approaches to Treatment of Addiction and Depression using Animal Models, please contact media@science.upd.edu.ph

Hands-on STEM learning in every home with VISSER

Hands-on STEM learning in every home with VISSER

Published: April 28, 2023

By: Eunice Jean C. Patron and Marie Asheidee M. Masayon

PHOTO CREDIT: making.technology

The Philippines has long lagged behind the rest of the world in terms of science, technology, engineering, and mathematics (STEM) learning: in 2018, the country was the second worst out of 79 countries worldwide in terms of the science and mathematics performance of high school students.

 

This dearth prompted physics professor and current Dean of the University of the Philippines – Diliman College of Science (UPD-CS) Dr. Giovanni A. Tapang to spearhead the Versatile Instrumentation System for Science Education and Research (VISSER).

 

This low-cost, portable handheld device that students can use for their laboratory experiments was developed in collaboration with researchers from UP Diliman and UP Los Baños, with support from the Department of Science and Technology (DOST) and the UP Diliman Office of the Vice President for Academic Affairs (UPD OVPAA).

 

“Gaining a better understanding of science requires laboratory experiments, but specific equipment is often expensive, making it difficult for some high schools in the Philippines to purchase necessary equipment,” Dr. Tapang said. “VISSER addresses this problem through low-priced modern digital tools for learning to help transform students’ curiosity into scientific competency and broaden their perspective by exploring the experiential aspect of science.”

PHOTO CREDIT: making.technology

VISSER aims to bring a modern science laboratory experience to high schools all over the country. Designed for students on a STEM track, the device allows for hands-on experiments in various subjects including physics, chemistry, biology, environmental science, and engineering.

 

In 2022 alone, close to a hundred schools across the country received VISSER kits. An improved version is in the works, for use in online classes and distance learning, aptly dubbed VISSER@Home.

 

Dr. Tapang will be talking at length about VISSER at the upcoming iStories webinar hosted by UPD-CS this coming April 24, 2023. Joined by VISSER co-inventor and PhD candidate Dwight Angelo Bruzon, the forum will tackle not just the ideation and development of VISSER, but also its mass production and distribution.

 

“Thirty-five percent of high schools in the Philippines have no laboratories. Meanwhile, among those with laboratories, 33% have no access to digital tools for learning. Our mission is to put modern laboratories in every school and college in the country,” Bruzon noted.

PHOTO CREDIT: making.technology

iStories is a series of innovation-themed talks, storytelling, and activities featuring local and international scientists. The initiative aims to ignite the creativity and inventiveness of young scientists not just from UPD-CS but from other institutes inside and outside UP.

 

The second session of iStories on April 24, 2023 (Monday) will be held on-site at the College of Science Admin Auditorium. Only participants outside Metro Manila will be allowed to join the forum via Zoom.

 

The iStories series is regularly scheduled for 3:00 pm every last Monday of the month. To join, you may register through this link https://bit.ly/3EocEmD. Subscription to the entire iStories webinar series is also possible through the same form. 

 

To learn more about VISSER, please visit https://ttbdo.up.edu.ph/technology/visser/ 

 

For inquiries about iStories, please message adride_staff@science.upd.edu.ph 

 

For interview requests and other media concerns, please contact media@science.upd.edu.ph 

UP Scientists feted for pioneering genomics work

UP Scientists feted for pioneering genomics work

Published: April 28, 2023

By: Eunice Jean C. Patron

(From L-R) PGC Executive Director Dr. Cynthia Saloma, DOST Undersecretary Dr. Leah Buendia, DOST Secretary Dr. Renato Solidum, DOH Director of Epidemiology Bureau Dr. Alethea De Guzman, and DA Biotech Program Office Director Dr. Claro Mingala discuss the latest developments in Philippine genomics. (Photo credit: Shedy Masayon, UPD-CS)

From shedding light on mythological creatures to helping fight crime, the Philippine-led study of the basic building blocks of life has come a very long way. Ever since the inception of the country’s genomics program in 2009, scientists from the University of the Philippines Diliman – College of Science (UPD-CS) have been advancing the country’s genomics research in many surprising ways.

  

UPD-CS scientists lead the way 

 

Major outbreaks worldwide, such as dengue, SARS, and H1N1, brought the Philippines to realize the vital role of genomic research in predicting, diagnosing, and treating diseases before they spread to a greater degree. 

 

In the same year that the Department of Science and Technology (DOST) set the country’s genomics agenda, UP established the Philippine Genome Center (PGC), which aims to improve the

quality of the lives of Filipinos through genomics-focused multidisciplinary research. PGC was founded by four scientists, two of whom are from the UPD-CS: Dr. Gisela Concepcion of the Marine Science Institute (MSI) and Dr. Cynthia Saloma of the National Institute of Molecular Biology and Biotechnology (NIMBB), who also currently serves as the Center’s Executive Director. 

 

UPD-CS scientists also helm the PGC’s Executive Committee: Institute of Biology’s (IB’s) Dr. Neil Andrew Bascos, Director of the Protein, Proteomics, and Metabolomics Facility, and Dr. Michael Velarde, Director of the Biobank Core Facility; and Natural Science Research Institute’s (NSRI’s) Dr. Maria Corazon De Ungria, Director of Biodiversity, Ethnicity, and Forensics. 

 

Genomics in justice, mythology, and beyond 

 

In DOST’s recent press conference, “From Labs to Lives: Impact of DOST-led Genomics Program in PH,” held on April 14 at the PGC, UPD-CS scientists presented and discussed the significant milestones and progress that the Philippines’ genomics program has achieved over the last decade. 

 

In particular, Dr. De Ungria showcased the NSRI DNA Analysis Laboratory’s locally-developed sexual assault investigation kit (SAIK) that doctors can use to facilitate justice for victims. The event also highlighted advances in understanding and testing for dystonia parkinsonism, a rare genetic disease thought to be the basis for the “aswang” creatures of Philippine mythology. The speakers also touched on new studies in improving the breed and stock of Philippine cows implemented by the Philippine Carabao Center. 

 

The event was capped by the unveiling of the PGC’s new Protein, Proteomics, and Metabolomics Facility (PPMF) that will enable the Center to further its research into the effects and end-products of genes’ functions in the body. 

 

Filipino researchers have vastly expanded genomics applications in health care in the Philippines in various ways. Through their pioneering research studies and contribution to the genomics program of the country, UPD-CS scientists continue to use science for national progress, embodying UP’s commitment to serving the Filipino people. 

 

For interview requests and other concerns, please contact media@science.upd.edu.ph.

Researchers urge oil spill cleanup amid calm weather

Researchers urge oil spill cleanup amid calm weather

Published: March 28, 2023

By: Timothy James M. Dimacali

Scientists from the University of the Philippines – Diliman Marine Science Institute (UPD-CS MSI) have noted a “window of opportunity” to step up efforts to clean up the oil spill from the MT Princess Empress tanker that sank off Naujan, Occidental Mindoro, last February 28.

 

 

“Weaker winds and calmer seas allow for larger oil slicks to form because of less disturbance from waves,” the researchers noted in their latest update. Satellite data from the US National Oceanographic and Atmospheric Administration (NOAA) as of March 21 showed that the floating oil had accumulated into a 37.84-square-kilometer slick—”larger than Las Piñas,” the scientists noted. 

 

The accumulated oil, along with the improved weather, may be a boon to cleanup efforts: “Calmer seas and larger slicks should be taken as an opportunity to collect the oil in slicks near the sunken tanker using booms and skimmers and ramp up cleanup efforts to prevent the oil from spreading further,” the UPD-CS MSI said.

 

The researchers also warned that, with the seasonal weakening of the Amihan Northeast Monsoon, the subsequent strengthening of  easterly winds may push the oil further westward through the Verde Island Passage (VIP), one of the most biodiverse regions in the world and home to thousands of unique species. With some of the highest concentrations of coastal fishes, corals, crustaceans, molluscs, seagrasses, and mangroves worldwide, the Passage is the main source of food and livelihood for millions of Filipinos.

 

For the full update and for notifications of new developments, please Like and subscribe to https://www.facebook.com/upmarinescienceinstitute 

 

The UPD-CS MSI is also asking the public for help in monitoring the oil spill. The public is encouraged to contribute geotagged images of sightings of the MT Princess Empress oil spill through this form: https://bit.ly/MTPE_GPS. The use of a GPS-enabled phone and a GPS camera app such as “GPS Map Camera” (available on Google Play and the Apple Store) are recommended so that geotag location data can be preserved. 

 

For interview requests and other media concerns, please contact media@science.upd.edu.ph 

Pinoy inventor jumpstarts monthly innovation forum

Pinoy inventor jumpstarts monthly innovation forum

Published: March 27, 2023

By: Timothy James M. Dimacali

Inventors revolutionize the world because they often see in a different light—sometimes literally so, as in the case of this Filipino scientist-entrepreneur.

Filipino biochemist and entrepreneur Dr. Carlito Lebrilla in his element. (Photo credit: Gregory Urquiaga, UCDavis)

A distinguished professor and biochemist, Dr. Carlito Lebrilla of the University of California, Davis (UC Davis) is also a corresponding member of the National Academy of Science and Technology (NAST). He will be highlighting his research on mass spectrometry and the fundamentals of innovation for startup companies at the free inaugural iStories webinar hosted by the University of the Philippines Diliman College of Science (UPD-CS) this coming March 27.

 

A business born from mass spectrometry

 

Dr. Lebrilla’s research is focused on understanding fundamental processes in the ionization, fragmentation, and detection of ions. This enabled him to build a complex Fourier transform ion cyclotron resonance (FTICR) mass spectrometer that marked the start of  a research and teaching career centered on mass spectrometry.

 

Mass spectrometry is an analytical technique used to identify and quantify compounds, and determine structure and chemical properties of molecules via molecular weight determination. Chemists can use a mass spectrometer to ionize a molecular compound in gaseous form, sort the fragments, and then identify the molecule fragments based on their molecular weights. Applications of mass spectrometry include determination of rock ages, biochemical evolution of the Earth, and space explorations.

 

In Dr. Lebrilla’s case, his work on mass spectrometry helped him transition into the biomedical field that led him to develop methods for characterizing glycoconjugates—the biochemicals that contain carbohydrates bonded to some other compounds such as protein and lipid—in cells, animals, and humans. 

 

Dr. Lebrilla’s further research and discoveries in mass spectrometry have led to several patents and the founding of at least five companies. “I realized there were so many problems that mass spectrometry can solve in food, in health, and even in basic fundamental biological issues. I just kept finding new ideas there, which really appealed to me,” he says in one interview with Journal of the American Society for Mass Spectronomy.

 

iStories: a monthly series on innovation

 

iStories is one of UPD-CS’s initiatives to lead more researchers and students to adopt the perception of nation-building through science, according to Dr. Ricky B. Nellas, the Associate Dean for Research, Innovation, Development, and Enterprise (ADRIDE) of the College of Science.

 

“Innovations, especially recent advances in the fields of data science and breakthroughs in technology, have accelerated our knowledge on relevant fields of science such as disease biology, artificial intelligence, and the knowledge-research-product pipeline. It is only paramount for us, especially young scientists, to be up to speed with current advances in science and technology. We hope that the iStories webinar series would motivate Filipino scientists to forge new collaborations in order to solve relevant and neglected local and worldwide problems, through innovation-centric research.” he explained.

 

iStories is a free webinar series with innovation-themed lectures, storytelling, and activities featuring local and international scientists. The initiative is aimed at igniting the creativity and inventiveness of young scientists not just from the College of Science, but from other institutes inside and outside UP.

 

“We started this initiative to showcase the different paths towards scientific innovations that can be emulated by our researchers and students in order to contribute to nation building,” says CS Innovation Team Head, Dr. Lerrie Ann Ipulan-Colet. The team is composed of innovation representatives from nine institutes under the UPD-CS.

 

iStories is scheduled for 3:00 pm every last Monday of the month.

 

Interested participants can register to the webinar via Zoom through filling out this online form: bit.ly/3EocEmD. Subscription to the entire iStories webinar is also possible through the same form. 

 

For interview requests and other concerns, please contact media@science.upd.edu.ph

References:

Brenner, A. & Simpson, H. (2021). Faces of Mass Spectrometry/Carlito Lebrilla. J. Am. Soc. Mass Spectrom. 2021, 32, 6, 1275–1277 https://doi.org/10.1021/jasms.1c00116

Irreplaceable marine resources of Verde Island Passageunder threat from oil spill

Irreplaceable marine resources of Verde Island Passage under threat from oil spill

Published: March 27, 2023

By: Timothy James M. Dimacali

The priceless marine resources and famously pristine beaches of the Verde Island Passage (VIP)  in the Southern Tagalog region remain under threat from swaths of  thick black oil from the MT Princess Empress tanker that sank off Naujan, Occidental Mindoro, last February 28.


Located between Batangas and Mindoro, the VIP is one of the most biodiverse regions in the world, home to thousands of unique species. With some of the highest concentrations of coastal fishes, corals, crustaceans, molluscs, seagrasses, and mangroves worldwide, it is the main source of food and livelihood for over seven million people. The area also encompasses Puerto Galera, whose white sand beaches are internationally-acclaimed tourist destinations that are another vital source of revenue for local communities.

Thick black oil has been found floating off the coast of Baco Chico Island near Calapan City, Oriental Mindoro. (Photo credit: Marion Cepillo, Blue Alliance Key Ocean Defender (BAKOD), Blue Alliance)

Experts from the University of the Philippines – Diliman College of Science Marine Science Institute (UPD-CS MSI) have been working closely around the clock with the Department of Environment and Natural Resources (DENR) and the Philippine Coast Guard (PCG) alongside other universities, government agencies, and stakeholders in a race to address the oil spill and stop it from spreading.


“The VIP is home to endangered and threatened species including the critically endangered hawksbill turtle, whale sharks, manta rays, dugongs, humphead wrasses, giant groupers, and giant clams,” the UPD-CS MSI said in an update. “Damage from the oil spill may affect biodiversity (including endemic species only found in the Philippines as well as species yet to be discovered), tourism revenues, and food security in the area,” they added.

The UPD-CS MSI’s forecast model for the week of March 17-26, 2023, shows that the MT Princess Empress oil spill may spread across the Verde Island Passage. Shown in the image are the possible trajectories for March 24. (Photo credit: UPD-CS MSI)

The UPD-CS MSI’s latest bulletin references a NOAA/NESDIS report based on satellite data which shows that oil was still leaking out of the sunken vessel as of March 19 and the visible oil slick is extending northwest towards the VIP.  

 

“The Verde Island Passage represents a large portion of the country’s marine biodiversity, and is a vital resource for millions of people, past and present,” said UPD-CS MSI Associate Professor Irene Rodriguez. “If we work together, we can still hopefully safeguard it for future generations to come.”

 

The UPD-CS MSI is asking the public for help in monitoring the oil spill. The public is encouraged to contribute geotagged images of sightings of the MT Princess Empress oil spill through this form: https://bit.ly/MTPE_GPS. The use of a GPS-enabled phone and a GPS camera app such as “GPS Map Camera” (available on Google Play and the Apple Store) are recommended so that geotag location data can be preserved. 

 

For interview requests and other media concerns, please contact media@science.upd.edu.ph 

Citizens’ photos of oil spill can help marine scientists save our seas

Citizens’ photos of oil spill can help marine scientists save our seas

Published: March 21, 2023

By: Timothy James M. Dimacali

Researchers are banking on Filipinos’ inherent love of photography and social media, bringing everyone together through collaborative “citizen science” to help save the country’s precious marine resources from the ravages of a recent disastrous oil spill.

The public is encouraged to send photos of the MT Princess Empress oil spill, along with a description and location to https://bit.ly/MTPE_GPS. Scientists can use this information to improve their understanding of the disaster and to make better forecast models. (Photo credit: UPD-CS SciComm)

The University of the Philippines – Diliman Marine Science Institute (UPD-CS MSI)  is rallying the public to use their mobile phones to help get a better idea of the extent of the oil spill from the tanker MT Princess Empress, which sank last February 28 off the coast of Naujan, Occidental Mindoro.

 

The simple act of taking a photo and uploading it along with the time and location will be used by the researchers as starting points for their forecast models, complemented by data from other sources including satellite images and computer simulations. (The submission form can be found here: https://bit.ly/MTPE_GPS)

 

“It’s as easy as uploading your favorite photo to social media,” said UPD-CS MSI Associate Professor Irene Rodriguez. “We need continuous monitoring for the presence of oil along the coasts to inform our models. All you have to do is send us your photo of the oil spill, along with when and where the picture was taken.”

A sample photograph from a concerned citizen pointing to spots of oil on a beach. The photographer also volunteered when and where the photo was taken, to help scientists develop more accurate forecasts. (Photo credit: Denmark Recamora / Blue Alliance)

The UPD-CS MSI’s team of experts has been working closely around the clock with the Department of Environment and Natural Resources (DENR) and the Philippine Coast Guard (PCG) alongside other universities, government agencies, and stakeholders in a race to address the MT Princess Empress oil spill and stop it from spreading.


Such public-sourced initiatives, often called “citizen science” and “citizen journalism,” are regularly used around the world to tap into the local knowledge of people on the ground to help build up a better understanding of oftentimes complex, large-scale phenomena.

 

The US Geological Survey’s (USGS’s) “Did You Feel It?”, for example, aggregates public responses and social media mentions to assess and understand the impact of recent earthquakes.  National Geographic Magazine also lists several citizen science initiatives in which even gradeschool kids can participate, from reef monitoring to space exploration.

 

Meanwhile, citizen journalism has long been a staple of online reportage in the Philippines as far back as 2009, when local news websites had to rely heavily on social media posts for updates on the aftermath of Typhoon Ondoy.


The public is encouraged to contribute geotagged images of the MT Princess Empress oil spill through this form: https://bit.ly/MTPE_GPS. The use of a GPS-enabled phone and a GPS camera app such as “GPS Map Camera” (available on Google Play and the Apple Store) are recommended so that geotag location data can be preserved. 


For interview requests and other media concerns, please contact media@science.upd.edu.ph 

UP scientists celebrate art and science as tools for healing and growth

UP scientists celebrate art and science as tools for healing and growth

Published: March 21, 2023

By: Eunice Jean C. Patron

Science and art have always been intertwined, but the intersection between them has never been more important than at the crossroads of history.

With the struggles and changes brought on by the COVID-19 pandemic still fresh in mind, scientists from the University of the Philippines – Diliman College of Science (UPD-CS) came together last February to look back on the things that helped them move above and beyond the bleakness of the times. Not surprisingly, art was a common denominator.

 

On February 24, UPD-CS’ free public webinar entitled “Intersections: How scientists use art to explore the world” featured speakers who told their personal stories to an audience of hundreds of people, many of whom were still reeling from years of lockdowns.

 

The panel consisted of the Institute of Biology’s (IB) Dr. Joyce Ibana, who paints flower art and children’s art to advocate for health and Dr. Erika Marie Bascos, who started painting during the pandemic as a form of therapy; Institute of Chemistry’s Dr. Hiyas Junio, who explores natural dyes through chemistry; the Institute of Environmental Science and Meteorology’s Dr. Benjamin Vallejo Jr., who writes prose and poetry on natural history.

 

Synergism from integrating art, science, and innovation

 

Dr. Ibana shared her journey in the realms of science, art, and innovation. “My journey in science is relatively straightforward, unlike art which I find more chaotic and uncertain. There are many unknowns and human factors [in art], but this is when I was more in touch with my humanity.”  She said innovation is a continuous iteration and prototyping process to improve things.

 

As a young girl, Dr. Ibana used to tag along with her parents, both educators in Daet, Camarines Norte. Seeing the chemicals and glassware in the school’s chemistry laboratory inspired her to become a chemist, which she proudly announced, to everyone’s surprise, during her graduation from Preparatory school. Even though she continued studying to become a scientist, her love for drawing and art remained in her blood, as she always illustrated models to explain her research.

 

Dr. Ibana’s study on Chlamydia trachomatis was used as the issue cover of the American journal “Infection and Immunity,” which she considered a significant milestone in her long journey as a scientist.

 

“What did you get out of this?” her mother asked her one day. “It was the most difficult question I’ve been asked in my whole journey as a scientist,” Dr. Ibana said. “My mother’s question prompted me to accept the invitation from the University of the Philippines to come home in 2013. Here, I found the joy of service in helping other younger generations of scientists realize their dream of becoming a scientist.”

 

The continuous pursuit of her research on Chlamydia trachomatis in the Philippines led Dr. Ibana to feel a strong desire to communicate the impact of science to humanity better. She painted flowers to express that Chlamydia is not a flower but a disease that can affect women and children. Some of her flower paintings were also included by an entrepreneur in one of their products. Dr. Ibana was fascinated with her ability to have something to give to the local industry.

 

“In science, our impact is based on citations. One of my most cited papers has 178 citations in about seven years. But when this one [art featured in products] happened, you give joy to many people, to 500 people [buyers of the products] in just three months. It’s very fascinating how art can impact people in a very small way,” Dr. Ibana said.

 

During the pandemic, Dr. Ibana created flowers and children’s art to highlight the importance of holistic health. She created art featuring COVID-19 and immunology and art that narrates the challenges of being a Filipino scientist.

 

In her training as a university innovation fellow, Dr. Ibana learned that putting science and innovation together solves real-world problems. Adding art to the mix communicates the science behind the innovation and promotes the innovation to the world. “Putting the realms of art, science, and innovation together in a nurturing and enabling environment, I hypothesize, is what allows us to make a better social impact.” 

 

Chemistry and colors in the context of local textiles

 

Dr. Junio’s extensive research on chemistry and natural dyes was a timely response to the surge in demand for natural dyes and textiles in the Philippines. In collaboration with the Philippine Textile Research Institute (PTRI), she assesses the quality of the natural indigo dyes produced from the Philippine indigo (Indigofera tinctoria). “Dyes from the Indigofera tinctoria are all considered indigo, but they actually have different colors. Some are pink, purple, or yellow. But it has something to do with the chemistry when they produce the dye.” 

 

According to Dr. Junio, the molecules of the indigo dye undergo different chemical processes that result in various indigo components, such as indigotin (the blue component), indirubin (the red component), and isoindigo (the yellow-orange component). When mixed, these components would form different shades of indigo. “We wanted to ensure that the ones [indigo] produced by the local community have a higher indigotin content than the indirubin and the isoindigo,” she added.

 

Dr. Junio’s research analyzes small molecules from different sources, such as marine and plant extracts. The extractions they use for natural dyes follow the procedure suggested by PTRI’s handbook. “The molecule is broken down into pieces, and from those pieces, we can identify the particular structure of the molecule by using a reference library,” she explained.

 

Her research on natural indigo dyes will help standardize the indigo dyes sold in the country. This will give the Philippines a competitive edge and the capability to sell indigo dye powders outside the country for economic gain.

 

Aside fromnatural indigo dyes, Dr. Junio also researched producing dyes from endemic Philippine plants, such as katmon (Dillenia philipinensis), mabolo (Diospyros discolor), Mindanao gum tree (Eucalyptus deglupta), makopa (Syzygium samarangense), and makopang-kalabaw (Syzygium malaccense).

 

Dr. Junio and her team plan to give the UP College of Fine Arts natural dyes, which the College can use for its artwork.

 

Healing using botanical art

 

Despite being constantly surrounded by botanical drawings through her Rafflesia research and by instructing students to draw plant specimens, Dr. Bascos had no experience with painting and the arts.

 

It all changed when her daughters asked her to paint with them during the pandemic. Her youngest daughter asked her to paint flowers. Dr. Bascos then posted her paintings on social media. She received a lot of positive feedback, which motivated her to resume painting. Eventually, Dr. Bascos fell in love with painting as it helped her deal with anxiety and depression.

 

“Painting gave me an hour of peace per day and it’s nice to know that even a chaotic mind is still capable of creating something pretty,” Dr. Bascos said. “I didn’t really care if what I was doing was right or not, the technique or whatsoever, I just painted all my anxieties away.”

 

At some point, people started asking her if they could buy or commission a particular artwork, but Dr. Bascos was having a lot of self-doubt about her painting skills. Then, she met Bing Famoso, founder of the Philippine Botanical Art Society and the Philippine Fauna Art Society. Famoso, who uses acrylic paint as her medium, asked her to teach her how to paint using watercolor. “Imagine, it’s the founder of all these art societies asking me if I could teach her how to paint using watercolor, and I felt validated. After talking with Ma’am Bing, I was confident to accept commissions or even sell my paintings,” Dr. Bascos narrated.

 

After a year of painting, Dr. Bascos was able to join an online botanical art exhibition hosted by the Philippine Botanical Art Society with her portrait of the Medinilla magnifica.

 

Even though Dr. Bascos studies the Raflessia species, it’s a flower she hasn’t tried painting yet. “I’m super intimidated by the Raflessia. I’m so scared that my painting will look like donuts.”

 

She advises people who want to try painting to just go for it. “Don’t be scared to try something different. I was in my mid-30s when I started painting. You’re never too old to try or learn something new,” Dr. Bascos advised. “If you want to go into botanical art, I suggest you use the actual plant specimen instead of photos because I feel that the colors are better if you see them in person.”

 

Perceiving creatures through literature

 

“One way to make [science] come alive is to put them in words,” said Dr. Vallejo as he showed a photo of a Sally Lightfoot crab, one of the species Nobel laureate John Steinbeck Jr. described in his travelogue, The Log from the Sea of Cortez. Dr. Vallejo opined that the environment provides material for writing prose; writers of natural history manuals even try to put their scientific observations into prose.

 

“This is the point about the arts, the humanities, and the sciences,” he explained. “They are ways of gaining knowledge about the world. Their approaches are rather different, but the impetus to do so is more or less the same.”

 

Dr. Vallejo also mentioned the works of marine biologist and writer Rachel Carson, whose books, such as Silent Spring influenced the global environmental movement. “We need science to improve, but the impetus to commit to improvement may be found in humanities with sciences in it,” he concluded. ###

 

The full video recording of “Intersections: How scientists use art to explore the world” can be found here: https://youtu.be/HcfuRM_OyWs 

 

For interview requests and other concerns, please contact media@science.upd.edu.ph 

New documentary offers hope for vanishing mangroves

New documentary offers hope for vanishing mangroves

Published: March 15, 2023

By: Eunice Jean C. Patron

Mangrove deforestation is a global crisis, but this scientist-turned-filmmaker has found hope in a small Southern Tagalog town where culture and nature intersect in surprising ways.
View the full teaser trailer of Dr. Lemnuel Aragones’ Bakawan here: https://youtu.be/VlnSo3gn73U. The documentary is set to have its free public premiere on March 27, 2023 (Monday), at 1:00 PM at the Institute of Biology (IB) Auditorium, UP Diliman.

The Philippines is the second worst country in terms of mangrove losses in the Association of Southeast Asian Nations (ASEAN): it suffered a 10.5% decline between 1990 and 2010, according to independent studies cited in a recent comprehensive survey. The country is surpassed only by Myanmar, which suffered a 27.6% loss between 2000 and 2014.

 

With mangrove decline continuing largely unchecked, coastal communities that have depended on these forests for generations face losing the heart not just of their food, fuel, shelter, and livelihood, but also of their very culture. But for Dr. Lemnuel Aragones, a marine biologist and former director of the University of the Philippines – Diliman College of Science Institute of Environmental Science and Meteorology (UPD-CS IESM), all is not yet lost.

Dr. Aragones’ debut documentary, Bakawan (the Tagalog term for mangroves), tells the story of the people of Alabat Island in Quezon Province, a five-hour drive and an hour’s ferry ride away from the nation’s capital. Shot during the COVID-19 pandemic lockdown, the film delves into the townspeoples’ renewed relationship with the mangroves that they call home. With the theme, “Kahalagahan, isyus, at pagpapanumbalik,” Bakawan explores the human story of living in and with Alabat’s estuarian mangrove forest.

 

A collaboration between Dr. Aragones and UP Film Institute Associate Professor and filmmaker Nick Deocampo, Bakawan is part of the IESM’s 20th founding anniversary celebration this year. It is the only science-oriented video among the ten entries to the UP Emerging Interdisciplinary Research Grant’s (EIDR’s) Cinema for Education: Rationalizing the Philippine Audio-visual Industry to Promote Inclusive Education Through Film Literacy.

Funded by the UP Office of the Vice President for Academic Affairs (OVPAA), the Cinema Education research project explored ways to improve audio-visual materials for Philippine schools, such as by looking at how documentaries could be used to supplement and augment existing teaching and learning methods.

 

The COVID-19 pandemic emphasized the need to improve the traditional Philippine education system, with educators and students around the globe relying on technology to teach and learn. With a vision to have an audio-visual industry that complements digital technology in creating educational content, Cinema for Education aims to integrate image-based learning, such as utilizing films and videos, and digital technologies into the current word-based Philippine education system.

 

“We are exploring ways to maximize the utility of cinema for education by promoting inclusive education in the Philippines,” Dr. Aragones explained.

The free public premiere of Bakawan will be on March 27, 2023 (Monday), at 1:00 PM at the Institute of Biology (IB) Auditorium, UP Diliman.

 

The full teaser trailer for Bakawan can be viewed here: https://youtu.be/VlnSo3gn73U

 

For interview requests and other inquiries, please contact media@science.upd.edu.ph