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	<title>SCIENCE &#8211; University of the Philippines Diliman</title>
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		<title>Bagong Aklat Pambata na Tampok ang Isang Pilipinang Siyentista, Inilunsad</title>
		<link>https://science.upd.edu.ph/bagong-aklat-pambata-na-tampok-ang-isang-pilipinang-siyentista-inilunsad/?utm_source=rss&#038;utm_medium=rss&#038;utm_campaign=bagong-aklat-pambata-na-tampok-ang-isang-pilipinang-siyentista-inilunsad</link>
		
		<dc:creator><![CDATA[craigs]]></dc:creator>
		<pubDate>Mon, 15 Jun 2026 09:20:40 +0000</pubDate>
				<category><![CDATA[Latest News]]></category>
		<guid isPermaLink="false">https://science.upd.edu.ph/?p=19760</guid>

					<description><![CDATA[<p>Inilathala ang pangatlong aklat pambata sa seryeng Sulong Agham. Tampok ng pinakabagong aklat si Dr. Gay Jane Perez, ang Direktor Heneral ng Philippine Space Agency (PhilSA) at propesor sa Institute of Environmental Science and Meteorology (IESM) sa Kolehiyo ng Agham sa UP Diliman.</p>
<p>The post <a href="https://science.upd.edu.ph/bagong-aklat-pambata-na-tampok-ang-isang-pilipinang-siyentista-inilunsad/">Bagong Aklat Pambata na Tampok ang Isang Pilipinang Siyentista, Inilunsad</a> first appeared on <a href="https://science.upd.edu.ph">SCIENCE - University of the Philippines Diliman</a>.</p>]]></description>
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			<h2 class="elementor-heading-title elementor-size-default">Bagong Aklat Pambata na Tampok ang Isang Pilipinang Siyentista, Inilunsad</h2>		</div>
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			<h2 class="elementor-heading-title elementor-size-default">Published: June 15, 2026 <br>
By: Eunice Jean C. Patron <br>
Translated by: Dr. Eizadora T. Yu</h2>		</div>
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				<p><span style="font-weight: 400;">Inilathala ang pangatlong aklat pambata sa seryeng Sulong Agham. Tampok ng pinakabagong aklat si Dr. Gay Jane Perez, ang Direktor Heneral ng Philippine Space Agency (PhilSA) at propesor sa Institute of Environmental Science and Meteorology (IESM) sa Kolehiyo ng Agham sa UP Diliman.</span></p><p> </p>					</div>
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										<img width="2560" height="1920" src="https://science.upd.edu.ph/wp-content/uploads/2026/06/IMG_4571-2-scaled.jpg" class="attachment-full size-full wp-image-19751" alt="" srcset="https://science.upd.edu.ph/wp-content/uploads/2026/06/IMG_4571-2-scaled.jpg 2560w, https://science.upd.edu.ph/wp-content/uploads/2026/06/IMG_4571-2-300x225.jpg 300w, https://science.upd.edu.ph/wp-content/uploads/2026/06/IMG_4571-2-1024x768.jpg 1024w, https://science.upd.edu.ph/wp-content/uploads/2026/06/IMG_4571-2-768x576.jpg 768w, https://science.upd.edu.ph/wp-content/uploads/2026/06/IMG_4571-2-1536x1152.jpg 1536w, https://science.upd.edu.ph/wp-content/uploads/2026/06/IMG_4571-2-2048x1536.jpg 2048w, https://science.upd.edu.ph/wp-content/uploads/2026/06/IMG_4571-2-1568x1176.jpg 1568w" sizes="(max-width: 2560px) 100vw, 2560px" />											<figcaption class="widget-image-caption wp-caption-text">Ang paglulunsad ng aklat na “Isang Puwang sa Kalawakan: Si Gay Jane Perez at ang Diwata-1” ay dinaluhan ni Dr. Perez, ng may-akda na si Eugene Evasco, at ng ilustrador na si Henrick Dulin. (Larawan mula kay Terence Craig Soroño)</figcaption>
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				<p><span style="font-weight: 400;">Namahagi ng pirmadong kopya ng “Isang Puwang sa Kalawakan: Si Gay Jane Perez at ang Diwata-1” sa mga dumalo sa paglulunsad nito noong Mayo 8, 2026, na ginanap sa bulwagan ng UPD-CS Admin Building. Dinaluhan ito ng mga mga panauhing pandangal na sina  Dr. Gay Jane Perez, may-akdang si Dr. Eugene Evasco, at ilustrador na si Henrick Dulin. Tinalakay sa aklat pambata ang buhay at mga nagawa ni Dr. Perez bilang pinuno ng pangkat na nasa likod ng Diwata-1, ang kauna-unahang microsatellite ng Pilipinas at ang unang satelayt na dinisenyo at ginawa ng mga Pilipino.</span></p><p> </p><p><span style="font-weight: 400;">Ang Palanca Hall of Fame awardee na si Dr. Evasco ang sumulat ng aklat. Nilarawan niya sa kwentong pambata ang salaysay ng isang makabayang siyentista na ang layunin ay hindi lamang ang sariling pag-unlad, kundi pati na rin ang paglilingkod sa bayan. Sa pamamagitan ng kwento ni Dr. Gay Perez, umaasa siyang makahikayat ito ng mga batang Pilipino na abutin ang kanilang mga pangarap at maging bahagi ng susunod na henerasyon ng mga siyentistang magdadala sa agham at pananaliksik ng Pilipinas sa mas mataas na antas. “Nais ko ng ipakita sa mga kabataan ang isang tunay halimbawa ng Pilipina na nakakamit ng malaking tagumpay,” aniya.</span></p><p> </p>					</div>
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				<p><span style="font-weight: 400;">Ibinahagi naman ni Dr. Perez ang kanyang saloobin sa pagkakaroon ng isang aklat pambata na tampok ang kanyang buhay. “Kung may isang salitang makakapaglarawan sa karanasang ito, iyon ay nakakapagpapakumbaba. Nagulat ako na may ganitong uri ng proyekto. Nang mabasa ko ang aklat, ay yun din ang unang pagkakataong nakita ko ang sarili kong kwento. Kakaiba ang pakiramdam dahil kapag ako ay nagkwekwento ng aking buhay, piling bahagi lamang ang naibabahagi ko. Ngunit sa kwentong sinulat ni Eugene- mula sa aking kabataan sa Naga, hanggang sa NASA at sa PhilSA, ay nagbigay ito sa akin ng mas malalim na pagpapahalaga sa aking pinagdaanan. Nakita ko ang aking kwento mula sa ibang pananaw,” aniya.</span></p><p> </p><p><span style="font-weight: 400;">Ibinahagi rin ni Dr. Perez na tulad ng maraming kabataan, itinuring niya noon ang sarili bilang isang ordinaryong tao. Hindi niya pinangarap maging siyentista sapagkat wala naman siyang kilalang siyentista noong siya ay bata pa. “Ang mensaheng nais kong ipaabot sa mga batang babasa ng aking kwento, ay kaya rin nilang makamit ito—at higit pa. Dumating ang mga oportunidad sa aking buhay, at naging handa akong yakapin ang mga ito at harapin ang mga hamon. Dahil doon, narating ko kung nasaan ako ngayon,” dagdag niya.</span></p><p> </p><p><span style="font-weight: 400;">Binigyang-diin din ni Dr. Perez na ang maagang pagkakaroon ng mga role models ay maaaring magbukas ng mas maraming oportunidad para sa mga batang babae na pumasok sa larangan ng Agham, Teknolohiya, Inhinyeriya, at Matematika (STEM). Habang lumalaki, ang mga babaeng siyentistang nakikita niya ay kadalasan lamang sa mga pelikula, at madalas pang inilalarawan bilang mga “baliw na siyentista” na magulo ang buhok. “Noong bata pa ako, sana ay mas marami akong naging role models—napakahalaga niyon. Nagpapasalamat ako na nang dumating ang panahon ng pagpapasya tungkol sa aking karera, ay nabigyan ako ng pagkakataong makatrabaho ang mga taong maaari kong tularan, at sila ang naging inspirasyon ko upang tahakin ang agham,” paggunita niya.</span></p><p> </p><p><span style="font-weight: 400;">Ayon naman kay Dr. Giovanni Tapang, dating Dekano ng UPD-CS, kaibigan at dating kasamahan  ni Dr. Perez sa National Institute of Physics (NIP), ipinakikita ng Isang Puwang sa Kalawakan kung gaano kahalaga ang agham at teknolohiya sa paghubog ng kinabukasan ng bansa. Binigyang-diin niya ang kahalagahan ng ambag ni Dr. Perez sa larangan ng agham pangkalawakan. Dagdag pa niya, ang aklat ay hindi lamang pagdiriwang ng mga tagumpay ni Dr. Perez kundi pagkilala rin na may lugar ang kababaihan sa larangan ng space science at STEM. “May kakayahan tayong angkinin ang maliit na puwang na iyon, palawakin ito, at ilantad para sa kapakinabangan ng Pilipinas,” pagtatapos ni Dr. Tapang.</span></p><p> </p><p><span style="font-weight: 400;">Nabuo ang serye ng mga aklat pambatang Sulong Agham sa pamamagitan ng pagtutulungan ng Kolehiyo ng Agham at Kolehiyo ng Arte at Literatura ng UP Diliman, at ng non-profit na organisasyong Supling Sining, Inc.</span></p><p> </p><p><span style="font-weight: 400;">Kabilang din sa iba pang aklat sa seryeng ito ang Ang Doktor ng Dagat, na tampok ang marine scientist na si Deo Florence Onda na isinulat ni Prof. Rosario Torres-Yu; at Ang Natatanging Ngaratngat, na tampok ang biologist na si Leonard Co na isinulat naman ni Prof. Mon Sy.</span></p>					</div>
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				<p> </p><p><b style="color: var( --e-global-color-text ); font-family: var( --e-global-typography-secondary-font-family ), Sans-serif; font-size: var( --e-global-typography-secondary-font-size ); letter-spacing: var( --e-global-typography-secondary-letter-spacing ); background-color: var(--global--color-background);"><i>For interview requests and other concerns, please contact </i></b><a style="font-family: var( --e-global-typography-secondary-font-family ), Sans-serif; font-size: var( --e-global-typography-secondary-font-size ); letter-spacing: var( --e-global-typography-secondary-letter-spacing );" href="mailto:media@science.upd.edu.ph"><b><i>media@science.upd.edu.ph</i></b></a><i style="color: var( --e-global-color-text ); font-family: var( --e-global-typography-secondary-font-family ), Sans-serif; font-size: var( --e-global-typography-secondary-font-size ); font-weight: var( --e-global-typography-secondary-font-weight ); letter-spacing: var( --e-global-typography-secondary-letter-spacing ); background-color: var(--global--color-background);">.</i></p>					</div>
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					</div><p>The post <a href="https://science.upd.edu.ph/bagong-aklat-pambata-na-tampok-ang-isang-pilipinang-siyentista-inilunsad/">Bagong Aklat Pambata na Tampok ang Isang Pilipinang Siyentista, Inilunsad</a> first appeared on <a href="https://science.upd.edu.ph">SCIENCE - University of the Philippines Diliman</a>.</p>]]></content:encoded>
					
		
		
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		<title>New Science-Themed Children’s Book Spotlights Filipina Scientist</title>
		<link>https://science.upd.edu.ph/new-science-themed-childrens-book-spotlights-filipina-scientist/?utm_source=rss&#038;utm_medium=rss&#038;utm_campaign=new-science-themed-childrens-book-spotlights-filipina-scientist</link>
		
		<dc:creator><![CDATA[craigs]]></dc:creator>
		<pubDate>Mon, 15 Jun 2026 09:17:35 +0000</pubDate>
				<category><![CDATA[Latest News]]></category>
		<guid isPermaLink="false">https://science.upd.edu.ph/?p=19749</guid>

					<description><![CDATA[<p>The Sulong Agham children’s book series on Filipino scientists has recently published its newest book featuring Dr. Gay Jane Perez, Director General of the Philippine Space Agency (PhilSA) and professor at the University of the Philippines – Diliman College of Science’s Institute of Environmental Science and Meteorology (UPD-CS IESM).</p>
<p>The post <a href="https://science.upd.edu.ph/new-science-themed-childrens-book-spotlights-filipina-scientist/">New Science-Themed Children’s Book Spotlights Filipina Scientist</a> first appeared on <a href="https://science.upd.edu.ph">SCIENCE - University of the Philippines Diliman</a>.</p>]]></description>
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			<h2 class="elementor-heading-title elementor-size-default">New Science-Themed Children’s Book Spotlights Filipina Scientist</h2>		</div>
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			<h2 class="elementor-heading-title elementor-size-default">Published: June 15, 2026 <br>
By: Eunice Jean C. Patron </h2>		</div>
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				<p><span style="font-weight: 400;">The Sulong Agham children’s book series on Filipino scientists has recently published its newest book featuring Dr. Gay Jane Perez, Director General of the Philippine Space Agency (PhilSA) and professor at the University of the Philippines – Diliman College of Science’s Institute of Environmental Science and Meteorology (UPD-CS IESM).</span></p><p> </p>					</div>
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										<img width="2560" height="1920" src="https://science.upd.edu.ph/wp-content/uploads/2026/06/IMG_4571-2-scaled.jpg" class="attachment-full size-full wp-image-19751" alt="" srcset="https://science.upd.edu.ph/wp-content/uploads/2026/06/IMG_4571-2-scaled.jpg 2560w, https://science.upd.edu.ph/wp-content/uploads/2026/06/IMG_4571-2-300x225.jpg 300w, https://science.upd.edu.ph/wp-content/uploads/2026/06/IMG_4571-2-1024x768.jpg 1024w, https://science.upd.edu.ph/wp-content/uploads/2026/06/IMG_4571-2-768x576.jpg 768w, https://science.upd.edu.ph/wp-content/uploads/2026/06/IMG_4571-2-1536x1152.jpg 1536w, https://science.upd.edu.ph/wp-content/uploads/2026/06/IMG_4571-2-2048x1536.jpg 2048w, https://science.upd.edu.ph/wp-content/uploads/2026/06/IMG_4571-2-1568x1176.jpg 1568w" sizes="(max-width: 2560px) 100vw, 2560px" />											<figcaption class="widget-image-caption wp-caption-text">The “Isang Puwang sa Kalawakan” book launch was graced by Dr. Gay Jane Perez, author Dr. Eugene Evasco, and illustrator Henrick Dulin. (Photo credit: Terence Craig Soroño)</figcaption>
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				<p><span style="font-weight: 400;">Limited signed copies of “Isang Puwang sa Kalawakan: Si Gay Jane Perez at ang Diwata-1” were distributed during its launch event held on May 8, 2026, at the lobby of the UPD-CS Administration Building. The event was graced by Dr. Gay Jane Perez, author Dr. Eugene Evasco, and illustrator Henrick Dulin. “Isang Puwang sa Kalawakan” explores Dr. Perez’s life and work as the leader of the team behind Diwata-1, the first Philippine microsatellite and the first satellite designed and built by Filipinos.</span></p><p> </p><p><span style="font-weight: 400;">Dr. Evasco, a Palanca Hall of Fame awardee, described the story as being about a “makabayang siyentista,” whose goal is not only personal advancement but also the service of the nation. Through Dr. Perez’s story, he hopes to inspire Filipino children to pursue their dreams, sparking the next generation of scientists who will carry Filipino science and research beyond the country. “I wanted to show young people a real Filipino woman reaching great heights,” he said.</span></p><p> </p>					</div>
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				<p><span style="font-weight: 400;">Meanwhile, Dr. Perez described the experience of having a children’s book featuring her life and work as humbling. “If there’s one adjective, that’s it. I was surprised that this kind of work exists. When I saw the narrative, it was also the first time I saw my own story. It felt strange because when I tell my story, I only tell parts of it—but what Eugene wrote, from my childhood in Naga to NASA to PhilSA, made me appreciate it deeply. I saw it from a different perspective,” she shared.</span></p><p> </p><p><span style="font-weight: 400;">Dr. Perez mentioned that, like many children, she considered herself ordinary back then. She did not dream of becoming a scientist because she didn’t know one. “The message I want to share with young readers is that they can also achieve this—and even more. Opportunities came my way, and I was ready to embrace them and take on the challenges. That led me to where I am now,” she added.</span></p><p> </p><p><span style="font-weight: 400;">Dr. Perez emphasized that early exposure to role models can open more opportunities for young girls to pursue careers in science, technology, engineering, and mathematics (STEM). Growing up, the only female scientists she saw were in movies, often depicted as “mad scientists” with messy hair. “When I was young, I wished I had more role models—it’s very important. I’m grateful that when I was making decisions about my career, I had the chance to work with people I could look up to, and that inspired me to pursue science,” she recalled.</span></p><p> </p><p><span style="font-weight: 400;">“[Isang Puwang sa Kalawakan] demonstrates how science and technology play an important role in building our country’s future,” Former UPD-CS Dean and Dr. Perez’s friend Dr. Giovanni Tapang said, underscoring the importance of her work in space science. He added that “Isang Puwang sa Kalawakan” is not merely a celebration of Dr. Perez’s achievements, but also a recognition that there is space for women in the STEM field. “We have the capacity to claim that small space, expand it, and bring it out into the open for the benefit of the Philippines,” Dr. Tapang concluded.</span></p><p> </p><p><span style="font-weight: 400;">The Sulong Agham children’s book series was born out of a collaboration between the UPD-CS, the non-profit organization Supling Sining, Inc. (SSI), and the UPD College of Arts and Letters Departamento ng Filipino at Panitikang Pilipino (UPD-CAL DFPP).</span></p><p><span style="font-weight: 400;">Other books in this book series include “Ang Doktor ng Dagat,” featuring marine scientist Dr. Deo Florence Onda and written by Dr. Rosario Torres-Yu, and “Ang Natatanging Ngaratngat,” featuring Filipino biologist Leonard Co and written by Mon Sy.</span></p>					</div>
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				<p> </p><p><b style="color: var( --e-global-color-text ); font-family: var( --e-global-typography-secondary-font-family ), Sans-serif; font-size: var( --e-global-typography-secondary-font-size ); letter-spacing: var( --e-global-typography-secondary-letter-spacing ); background-color: var(--global--color-background);"><i>For interview requests and other concerns, please contact </i></b><a style="font-family: var( --e-global-typography-secondary-font-family ), Sans-serif; font-size: var( --e-global-typography-secondary-font-size ); letter-spacing: var( --e-global-typography-secondary-letter-spacing );" href="mailto:media@science.upd.edu.ph"><b><i>media@science.upd.edu.ph</i></b></a><i style="color: var( --e-global-color-text ); font-family: var( --e-global-typography-secondary-font-family ), Sans-serif; font-size: var( --e-global-typography-secondary-font-size ); font-weight: var( --e-global-typography-secondary-font-weight ); letter-spacing: var( --e-global-typography-secondary-letter-spacing ); background-color: var(--global--color-background);">.</i></p>					</div>
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					</div><p>The post <a href="https://science.upd.edu.ph/new-science-themed-childrens-book-spotlights-filipina-scientist/">New Science-Themed Children’s Book Spotlights Filipina Scientist</a> first appeared on <a href="https://science.upd.edu.ph">SCIENCE - University of the Philippines Diliman</a>.</p>]]></content:encoded>
					
		
		
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		<title>Ugnayan ng Paggamit ng Lupa at mga Virus sa Lamok, Natuklasan sa Pag-aaral ng UP</title>
		<link>https://science.upd.edu.ph/ugnayan-ng-paggamit-ng-lupa-at-mga-virus-sa-lamok-natuklasan-sa-pag-aaral-ng-up/?utm_source=rss&#038;utm_medium=rss&#038;utm_campaign=ugnayan-ng-paggamit-ng-lupa-at-mga-virus-sa-lamok-natuklasan-sa-pag-aaral-ng-up</link>
		
		<dc:creator><![CDATA[craigs]]></dc:creator>
		<pubDate>Tue, 09 Jun 2026 09:30:08 +0000</pubDate>
				<category><![CDATA[Latest News]]></category>
		<guid isPermaLink="false">https://science.upd.edu.ph/?p=19736</guid>

					<description><![CDATA[<p>Ang mga lamok tulad ng Aedes aegypti at Aedes albopictus, na kilalang naglilipat ng mga sakit gaya ng dengue, Zika, at chikungunya, ay maaaring may taglay na higit pa sa mga virus na nakakaapekto sa tao. Nagtataglay din sila ng mga insect-specific virus (mga virus na para lang sa insekto) na hindi nakakahawa sa tao; ang ilan pa nga sa mga ito ay maaaring pumigil sa pagdami ng mga virus na nagdudulot ng sakit. Nagpapahiwatig ito na ang mga lamok ay maaaring magsilbing mahalagang kagamitan sa pagtukoy ng mga kilala at umuusbong na virus na maaaring makaapekto sa kalusugan ng publiko.</p>
<p>The post <a href="https://science.upd.edu.ph/ugnayan-ng-paggamit-ng-lupa-at-mga-virus-sa-lamok-natuklasan-sa-pag-aaral-ng-up/">Ugnayan ng Paggamit ng Lupa at mga Virus sa Lamok, Natuklasan sa Pag-aaral ng UP</a> first appeared on <a href="https://science.upd.edu.ph">SCIENCE - University of the Philippines Diliman</a>.</p>]]></description>
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			<h2 class="elementor-heading-title elementor-size-default">Ugnayan ng Paggamit ng Lupa at mga Virus sa Lamok, Natuklasan sa Pag-aaral ng UP </h2>		</div>
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			<h2 class="elementor-heading-title elementor-size-default">Published: June 9, 2026 <br>
By: Eunice Jean C. Patron  <br>
Translated by: Mary Ann Corrales</h2>		</div>
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										<img width="484" height="512" src="https://science.upd.edu.ph/wp-content/uploads/2026/06/Virome-Image.png" class="attachment-full size-full wp-image-19732" alt="" srcset="https://science.upd.edu.ph/wp-content/uploads/2026/06/Virome-Image.png 484w, https://science.upd.edu.ph/wp-content/uploads/2026/06/Virome-Image-284x300.png 284w" sizes="(max-width: 484px) 100vw, 484px" />											<figcaption class="widget-image-caption wp-caption-text">Virome sequencing performed on Aedes aegypti and Ae. albopictus used in the study in 2018 revealed
sequences belonging to vertebrate-associated and insect-specific viruses (Asin et al,. 2025).</figcaption>
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				<p><span style="font-weight: 400;">Ang mga lamok tulad ng </span><i><span style="font-weight: 400;">Aedes aegypti </span></i><span style="font-weight: 400;">at </span><i><span style="font-weight: 400;">Aedes albopictus</span></i><span style="font-weight: 400;">, na kilalang naglilipat ng mga sakit gaya ng dengue, Zika, at chikungunya, ay maaaring may taglay na higit pa sa mga virus na nakakaapekto sa tao. Nagtataglay din sila ng mga </span><i><span style="font-weight: 400;">insect-specific virus </span></i><span style="font-weight: 400;">(mga virus na para lang sa insekto) na hindi nakakahawa sa tao; ang ilan pa nga sa mga ito ay maaaring pumigil sa pagdami ng mga virus na nagdudulot ng sakit. Nagpapahiwatig ito na ang mga lamok ay maaaring magsilbing mahalagang kagamitan sa pagtukoy ng mga kilala at umuusbong na virus na maaaring makaapekto sa kalusugan ng publiko. </span></p><p> </p><p><span style="font-weight: 400;">Sina Irish Coleen Asin, John Michael Egana, at Dr. Ma. Anita Bautista mula sa National Institute of Molecular Biology and Biotechnology ng University of the Philippines Diliman College of Science (UPD-CS NIMBB), kasama si Dr. Richard Paul ng Institut Pasteur, Université Paris Cité, ay nangolekta ng mga lamok mula sa tatlong lugar sa Los Baños, Laguna na nagkakaiba sa topograpiya at paggamit ng lupa. Gamit ang </span><i><span style="font-weight: 400;">viral metagenomics</span></i><span style="font-weight: 400;">—isang pamamaraan na tumutukoy sa lahat ng virus sa isang sampol—sinuri nila ang </span><i><span style="font-weight: 400;">virome </span></i><span style="font-weight: 400;">(kabuuan ng mga virus) sa loob ng mga lamok. </span></p><p> </p><p><span style="font-weight: 400;">Natuklasan sa kanilang pananaliksik na ang mga lamok ay nagtataglay ng mga virus mula sa 12 magkakaibang </span><i><span style="font-weight: 400;">taxon group</span></i><span style="font-weight: 400;">. Karamihan sa mga ito ay mga </span><i><span style="font-weight: 400;">insect-specific virus </span></i><span style="font-weight: 400;">(ISV). Pareho ring taglay ng </span><i><span style="font-weight: 400;">A. aegypti </span></i><span style="font-weight: 400;">at </span><i><span style="font-weight: 400;">A. albopictus </span></i><span style="font-weight: 400;">ang malaking bahagi ng mga natukoy na virus. </span></p><p> </p><p><span style="font-weight: 400;">Nangolekta ang mga </span><i><span style="font-weight: 400;">molecular biologist </span></i><span style="font-weight: 400;">ng mga sampol ng lamok mula sa tatlong barangay sa Los Baños, Laguna: ang Bagong Silang, Lalakay, at Bayog. Ang Bagong Silang ang </span><i><span style="font-weight: 400;">upstream </span></i><span style="font-weight: 400;">(bundok) na site, na matatagpuan 305–331 metro sa itaas ng antas ng dagat (</span><i><span style="font-weight: 400;">asl</span></i><span style="font-weight: 400;">), at may maburol na tanawin (</span><i><span style="font-weight: 400;">rolling landscape</span></i><span style="font-weight: 400;">). Ang Lalakay naman ang </span><i><span style="font-weight: 400;">midstream </span></i><span style="font-weight: 400;">na site—na nailalarawan sa pagkakaroon ng maburol hanggang sa medyo hindi pantay na lupain. Ang Bayog, na siyang tabing-lawa na site (</span><i><span style="font-weight: 400;">lakeshore site</span></i><span style="font-weight: 400;">), ay may patag na lupain. </span></p><p> </p><p><span style="font-weight: 400;">&#8220;Batay sa mga </span><i><span style="font-weight: 400;">land cover map</span></i><span style="font-weight: 400;">, napanatili ng Bagong Silang ang </span><i><span style="font-weight: 400;">forest cover </span></i><span style="font-weight: 400;">nito sa nakalipas na apat na dekada hanggang sa petsa ng pag-aaral. Sa kaparehong panahon, kapwa sumailalim ang Lalakay at Bayog sa konbersiyon mula sa pagiging agrikultural patungo sa mga </span><i><span style="font-weight: 400;">built-up area </span></i><span style="font-weight: 400;">(mga may estruktura at pamayanan),&#8221; pagbabahagi nila. </span></p><p> </p><p><span style="font-weight: 400;">Ipinakita rito sa pag-aaral na mas maraming uri ng virus ang natagpuan sa mga lugar na nabago na ng aktibidad ng tao—tulad ng mga urbanisado o nakalbong lupa, gaya ng mga Barangay Lalakay at Bayog—kumpara sa kagubatan ng Bagong Silang. &#8220;Ang mga lamok na ito ay kadalasang matatag sa mga pagbabago sa kapaligiran (</span><i><span style="font-weight: 400;">disturbance-resilient</span></i><span style="font-weight: 400;">), at mas mabisang host para sa iba&#8217;t ibang uri o </span><i><span style="font-weight: 400;">strain </span></i><span style="font-weight: 400;">ng virus,&#8221; dagdag pa ng mga </span><i><span style="font-weight: 400;">molecular biologist</span></i><span style="font-weight: 400;">. Kapansin-pansin na hindi nakita ng pangkat ang mga virus ng dengue, Zika, o chikungunya sa mga sampol. Gayunpaman, natuklasan na ang mga lamok mula sa dalawang barangay ay nagtataglay ng </span><i><span style="font-weight: 400;">Cell Fusing Agent Virus </span></i><span style="font-weight: 400;">(CFAV). Ang CFAV ay pinaniniwalaang pumipigil sa pagdami ng mga virus ng Dengue at Zika.</span></p><p> </p><p><span style="font-weight: 400;">&#8220;Ang potensyal na panganib ng mga umuusbong at posibleng hindi pa kilalang banta ng </span><i><span style="font-weight: 400;">arbovirus </span></i><span style="font-weight: 400;">ay nangangailangan ng mas pinalakas na mga programa sa pagsubaybay (</span><i><span style="font-weight: 400;">surveillance</span></i><span style="font-weight: 400;">) at </span><i><span style="font-weight: 400;">advanced </span></i><span style="font-weight: 400;">na pananaliksik sa mga </span><i><span style="font-weight: 400;">arboviral disease</span></i><span style="font-weight: 400;">—mga sakit na naililipat ng mga insekto tulad ng lamok,&#8221; ayon sa kanila. Binigyang-diin din nila na ang mga programa sa pagsubaybay sa </span><i><span style="font-weight: 400;">arbovirus </span></i><span style="font-weight: 400;">ay mahalaga sa kalusugan ng publiko, dahil binabantayan ang aktibidad ng mga lokal (</span><i><span style="font-weight: 400;">endemic</span></i><span style="font-weight: 400;">) at umuusbong na virus sa </span><i><span style="font-weight: 400;">real-time </span></i><span style="font-weight: 400;">upang makatulong sa pamamahala ng mga </span><i><span style="font-weight: 400;">outbreak</span></i><span style="font-weight: 400;">. Ang ganitong pagsubaybay ay maaaring mapahusay sa pamamagitan ng mga teknik ng </span><i><span style="font-weight: 400;">next-generation sequencing</span></i><span style="font-weight: 400;">, kabilang ang </span><i><span style="font-weight: 400;">virome sequencing</span></i><span style="font-weight: 400;">.</span></p><p> </p><p><span style="font-weight: 400;">Nabanggit din ng mga </span><i><span style="font-weight: 400;">molecular biologist </span></i><span style="font-weight: 400;">na ang mga lamok ay maaaring magsilbing mahalagang biyolohikal na target para sa mga programa sa pagsubaybay sa mga sakit na </span><i><span style="font-weight: 400;">zoonotic </span></i><span style="font-weight: 400;">at </span><i><span style="font-weight: 400;">arboviral</span></i><span style="font-weight: 400;">. &#8220;Ang mga lamok ay kumikilos na parang mga biyolohikal na heringgilya (</span><i><span style="font-weight: 400;">biological syringes</span></i><span style="font-weight: 400;">) na sumisipsip ng dugo sa iba&#8217;t ibang uri ng host,&#8221; itinala ng pangkat. &#8220;Dahil dito, maaari silang magbigay ng mahahalagang kaalaman ukol sa pagkakaiba-iba ng virus sa iba&#8217;t ibang espasyo, panahon, at uri ng hayop (</span><i><span style="font-weight: 400;">species</span></i><span style="font-weight: 400;">).&#8221;</span></p><p> </p><p><span style="font-weight: 400;">Ang kanilang pag-aaral na pinamagatang </span><i><span style="font-weight: 400;">&#8220;Virome sequencing and analysis of Aedes aegypti and Aedes albopictus from ecologically different sites in the Philippines&#8221; </span></i><span style="font-weight: 400;">ay nailathala sa </span><i><span style="font-weight: 400;">Parasites &amp; Vectors</span></i><span style="font-weight: 400;">. Ang internasyonal na journal na ito ay nakatuon sa lahat ng aspeto ng biyolohiya ng mga parasitiko, mga sakit na parasitiko, mga </span><i><span style="font-weight: 400;">intermediate host</span></i><span style="font-weight: 400;">, </span><i><span style="font-weight: 400;">vectors</span></i><span style="font-weight: 400;">, at mga </span><i><span style="font-weight: 400;">pathogen </span></i><span style="font-weight: 400;">na dala ng </span><i><span style="font-weight: 400;">vector</span></i><span style="font-weight: 400;">. Ang kanilang gawa ay sinuportahan ng Department of Science and Technology–Philippine Council for Health Research and Development (DOST-PCHRD) at ng UPD Office of the Vice Chancellor for Research and Development. </span></p><p> </p><p><b>Sanggunian</b><span style="font-weight: 400;">: <br /></span><span style="font-weight: 400;">Asin, I. C., Egana, J. M., Paul, R. E., &amp; Bautista, M. A. (2025). Virome sequencing and analysis of Aedes aegypti and Aedes albopictus from ecologically different sites in the Philippines. Parasites &amp; Vectors, 18(1). https://doi.org/10.1186/s13071-025-07073-7</span></p>					</div>
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				<p> </p><p><b style="color: var( --e-global-color-text ); font-family: var( --e-global-typography-secondary-font-family ), Sans-serif; font-size: var( --e-global-typography-secondary-font-size ); letter-spacing: var( --e-global-typography-secondary-letter-spacing ); background-color: var(--global--color-background);"><i>For interview requests and other concerns, please contact </i></b><a style="font-family: var( --e-global-typography-secondary-font-family ), Sans-serif; font-size: var( --e-global-typography-secondary-font-size ); letter-spacing: var( --e-global-typography-secondary-letter-spacing );" href="mailto:media@science.upd.edu.ph"><b><i>media@science.upd.edu.ph</i></b></a><i style="color: var( --e-global-color-text ); font-family: var( --e-global-typography-secondary-font-family ), Sans-serif; font-size: var( --e-global-typography-secondary-font-size ); font-weight: var( --e-global-typography-secondary-font-weight ); letter-spacing: var( --e-global-typography-secondary-letter-spacing ); background-color: var(--global--color-background);">.</i></p>					</div>
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					</div><p>The post <a href="https://science.upd.edu.ph/ugnayan-ng-paggamit-ng-lupa-at-mga-virus-sa-lamok-natuklasan-sa-pag-aaral-ng-up/">Ugnayan ng Paggamit ng Lupa at mga Virus sa Lamok, Natuklasan sa Pag-aaral ng UP</a> first appeared on <a href="https://science.upd.edu.ph">SCIENCE - University of the Philippines Diliman</a>.</p>]]></content:encoded>
					
		
		
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		<title>How Land Use Shapes the Viruses Mosquitoes Carry, UP Study Finds</title>
		<link>https://science.upd.edu.ph/how-land-use-shapes-the-viruses-mosquitoes-carry-up-study-finds/?utm_source=rss&#038;utm_medium=rss&#038;utm_campaign=how-land-use-shapes-the-viruses-mosquitoes-carry-up-study-finds</link>
		
		<dc:creator><![CDATA[craigs]]></dc:creator>
		<pubDate>Tue, 09 Jun 2026 09:27:11 +0000</pubDate>
				<category><![CDATA[Latest News]]></category>
		<guid isPermaLink="false">https://science.upd.edu.ph/?p=19730</guid>

					<description><![CDATA[<p>Mosquitoes such as Aedes aegypti and Aedes albopictus, which are known to transmit diseases like dengue, Zika, and chikungunya, may carry more than just viruses that affect humans. They also host insect-specific viruses that do not infect people, some of which may even inhibit the multiplication of disease-causing viruses. This implies that mosquitoes can serve as valuable tools for detecting both known and emerging viruses that may impact public health.</p>
<p>The post <a href="https://science.upd.edu.ph/how-land-use-shapes-the-viruses-mosquitoes-carry-up-study-finds/">How Land Use Shapes the Viruses Mosquitoes Carry, UP Study Finds</a> first appeared on <a href="https://science.upd.edu.ph">SCIENCE - University of the Philippines Diliman</a>.</p>]]></description>
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			<h2 class="elementor-heading-title elementor-size-default">How Land Use Shapes the Viruses Mosquitoes Carry, UP Study Finds</h2>		</div>
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			<h2 class="elementor-heading-title elementor-size-default">Published: June 9, 2026 <br>
By: Eunice Jean C. Patron </h2>		</div>
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										<img width="484" height="512" src="https://science.upd.edu.ph/wp-content/uploads/2026/06/Virome-Image.png" class="attachment-full size-full wp-image-19732" alt="" srcset="https://science.upd.edu.ph/wp-content/uploads/2026/06/Virome-Image.png 484w, https://science.upd.edu.ph/wp-content/uploads/2026/06/Virome-Image-284x300.png 284w" sizes="(max-width: 484px) 100vw, 484px" />											<figcaption class="widget-image-caption wp-caption-text">Virome sequencing performed on Aedes aegypti and Ae. albopictus used in the study in 2018 revealed
sequences belonging to vertebrate-associated and insect-specific viruses (Asin et al,. 2025).</figcaption>
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				<p><span style="font-weight: 400;">Mosquitoes such as </span><i><span style="font-weight: 400;">Aedes aegypti</span></i><span style="font-weight: 400;"> and </span><i><span style="font-weight: 400;">Aedes albopictus</span></i><span style="font-weight: 400;">, which are known to transmit diseases like dengue, Zika, and chikungunya, may carry more than just viruses that affect humans. They also host insect-specific viruses that do not infect people, some of which may even inhibit the multiplication of disease-causing viruses. This implies that mosquitoes can serve as valuable tools for detecting both known and emerging viruses that may impact public health.</span></p><p> </p><p><span style="font-weight: 400;">Irish Coleen Asin, John Michael Egana, and Dr. Ma. Anita Bautista of the University of the Philippines – Diliman College of Science’s National Institute of Molecular Biology and Biotechnology (UPD-CS NIMBB), together with Dr. Richard Paul of Institut Pasteur, Université Paris Cité, collected mosquitoes from three areas in Los Baños, Laguna that differ in topography and land use. Using viral metagenomics—a method that identifies all viruses in a sample—they analyzed the virome inside the mosquitoes.</span></p><p> </p><p><span style="font-weight: 400;">Their research revealed that the mosquitoes carried viruses from 12 different taxon groups. Most of these were insect-specific viruses (ISVs), which infect mosquitoes but not humans. Both </span><i><span style="font-weight: 400;">A. aegypti</span></i><span style="font-weight: 400;"> and </span><i><span style="font-weight: 400;">A. albopictus</span></i><span style="font-weight: 400;"> also shared the majority of the identified viruses.</span></p><p><span style="font-weight: 400;">The molecular biologists collected mosquito samples from three barangays in Los Baños, Laguna: Bagong Silang, Lalakay, and Bayog. Bagong Silang is the upstream (mountain) site, located 305–331 meters above sea level (asl), with a rolling landscape. Lalakay is the midstream site—characterized by rolling to slightly uneven terrain. Bayog, the lakeshore site, has a flat landscape.</span></p><p><span style="font-weight: 400;">“Based on the land cover maps, Bagong Silang retained its forest cover in the last 4 decades as of the study date. At the same time, both Lalakay and Bayog underwent conversion from agricultural to built-up areas during that period,” they shared.</span></p><p> </p><p><span style="font-weight: 400;">The study also showed that more types of viruses were found in areas altered by human activity—such as urban or cleared land, like Barangays Lalakay and Bayog—compared to the forested area of Bagong Silang. “These mosquitoes are usually disturbance-resilient and are more competent hosts for several viral isolates or strains,” the molecular biologists added. Notably, the team did not detect dengue, Zika, or chikungunya viruses in the samples. Interestingly, mosquitoes from two barangays were found to harbor the Cell Fusing Agent Virus (CFAV). CFAV has been thought to inhibit the proliferation of Dengue and Zika viruses.</span></p><p> </p><p><span style="font-weight: 400;">“The potential risk of emerging and possibly unknown arboviral threats calls for strengthened surveillance programs and advanced research on arboviral diseases—those transmitted by insects like mosquitoes,” they said, emphasizing that arbovirus surveillance programs are vital to public health, as they monitor the activity of both endemic and emerging viruses in real time to help manage outbreaks. Such monitoring can be enhanced through next-generation sequencing techniques, including virome sequencing.</span></p><p> </p><p><span style="font-weight: 400;">The molecular biologists also noted that mosquitoes may serve as important biological targets for zoonotic and arboviral disease surveillance programs. “Mosquitoes act like biological syringes, feeding on multiple kinds of hosts,” the team pointed out. “Because of this, they can provide valuable insights into viral diversity across space, time, and species.”</span></p><p> </p><p><span style="font-weight: 400;">Their study, “Virome sequencing and analysis of </span><i><span style="font-weight: 400;">Aedes aegypti</span></i><span style="font-weight: 400;"> and </span><i><span style="font-weight: 400;">Aedes albopictus</span></i><span style="font-weight: 400;"> from ecologically different sites in the Philippines,” was published in </span><i><span style="font-weight: 400;">Parasites &amp; Vectors</span></i><span style="font-weight: 400;">. This international journal focuses on all aspects of the biology of parasites, parasitic diseases, intermediate hosts, vectors, and vector-borne pathogens. Their work was supported by the Department of Science and Technology—Philippine Council for Health Research and Development (DOST-PCHRD) and the UPD Office of the Vice Chancellor for Research and Development.</span></p><p> </p><p><b>References:</b></p><p><span style="font-weight: 400;">Asin, I. C., Egana, J. M., Paul, R. E., &amp; Bautista, M. A. (2025). Virome sequencing and analysis of </span><i><span style="font-weight: 400;">Aedes aegypti</span></i><span style="font-weight: 400;"> and </span><i><span style="font-weight: 400;">Aedes albopictus </span></i><span style="font-weight: 400;">from ecologically different sites in the Philippines. </span><i><span style="font-weight: 400;">Parasites &amp; Vectors</span></i><span style="font-weight: 400;">, </span><i><span style="font-weight: 400;">18</span></i><span style="font-weight: 400;">(1). </span><a href="https://doi.org/10.1186/s13071-025-07073-7"><span style="font-weight: 400;">https://doi.org/10.1186/s13071-025-07073-7</span></a></p>					</div>
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					</div><p>The post <a href="https://science.upd.edu.ph/how-land-use-shapes-the-viruses-mosquitoes-carry-up-study-finds/">How Land Use Shapes the Viruses Mosquitoes Carry, UP Study Finds</a> first appeared on <a href="https://science.upd.edu.ph">SCIENCE - University of the Philippines Diliman</a>.</p>]]></content:encoded>
					
		
		
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		<title>Mga Pilipinong Siyentipiko Gumawa ng Novel Method upang Pagbutihin ang mga Mathematical Model upang Makatuklas ng Drug Targets</title>
		<link>https://science.upd.edu.ph/mga-pilipinong-siyentipiko-gumawa-ng-novel-method-upang-pagbutihin-ang-mga-mathematical-model-upang-makatuklas-ng-drug-targets/?utm_source=rss&#038;utm_medium=rss&#038;utm_campaign=mga-pilipinong-siyentipiko-gumawa-ng-novel-method-upang-pagbutihin-ang-mga-mathematical-model-upang-makatuklas-ng-drug-targets</link>
		
		<dc:creator><![CDATA[craigs]]></dc:creator>
		<pubDate>Fri, 29 May 2026 05:10:55 +0000</pubDate>
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					<description><![CDATA[<p>Ang mga biological process na tulad ng Wnt signaling pathway—na nangangasiwa sa critical development at makakatulong na panatilihing normal at balanse ang mga tissue ng katawan—ay kadalasang inilalarawan ng mga siyentipiko gamit ang mga mathematical map na tinatawag na mga reaction network, na nagsisilbing pundasyon ng mga mathematical model. Nagbibigay-daan ito sa mga siyentipiko na suriin at paghambingin ang mga modelo batay lamang sa kanilang istruktura nang hindi nangangailangan man ng o bahagyang may mga specific parameter value. Bagaman may ilan ng Wnt models, nagkakaiba sila sa kung paano nila kinakatawan ang iisang underlying biological system. Upang matugunan ito, may ilang Filipino mathematicians ang nagpakilala ng isang bagong paraan upang matumbok ang common ground sa pagitan ng mga mathematical map na ito.</p>
<p>The post <a href="https://science.upd.edu.ph/mga-pilipinong-siyentipiko-gumawa-ng-novel-method-upang-pagbutihin-ang-mga-mathematical-model-upang-makatuklas-ng-drug-targets/">Mga Pilipinong Siyentipiko Gumawa ng Novel Method upang Pagbutihin ang mga Mathematical Model upang Makatuklas ng Drug Targets</a> first appeared on <a href="https://science.upd.edu.ph">SCIENCE - University of the Philippines Diliman</a>.</p>]]></description>
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			<h2 class="elementor-heading-title elementor-size-default">Mga Pilipinong Siyentipiko Gumawa ng Novel Method upang Pagbutihin ang mga Mathematical Model upang Makatuklas ng Drug Targets</h2>		</div>
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			<h2 class="elementor-heading-title elementor-size-default">Published: May 29, 2026 <br>
By: Eunice Jean C. Patron <br>
Translated by: Dr. Ian Kendrich C. Fontanilla</h2>		</div>
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			<h2 class="elementor-heading-title elementor-size-default">Ang mga biological process na tulad ng Wnt signaling pathway—na nangangasiwa sa critical development at makakatulong na panatilihing normal at balanse ang mga tissue ng katawan—ay kadalasang inilalarawan ng mga siyentipiko gamit ang mga mathematical map na tinatawag na mga reaction network, na nagsisilbing pundasyon ng mga mathematical model. Nagbibigay-daan ito sa mga siyentipiko na suriin at paghambingin ang mga modelo batay lamang sa kanilang istruktura nang hindi nangangailangan man ng o bahagyang may mga specific parameter value. Bagaman may ilan ng Wnt models, nagkakaiba sila sa kung paano nila kinakatawan ang iisang underlying biological system. Upang matugunan ito, may ilang Filipino mathematicians ang nagpakilala ng isang bagong paraan upang matumbok ang common ground sa pagitan ng mga mathematical map na ito.
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										<img width="1152" height="896" src="https://science.upd.edu.ph/wp-content/uploads/2026/05/CSEN-figure.png" class="attachment-full size-full wp-image-19673" alt="" srcset="https://science.upd.edu.ph/wp-content/uploads/2026/05/CSEN-figure.png 1152w, https://science.upd.edu.ph/wp-content/uploads/2026/05/CSEN-figure-300x233.png 300w, https://science.upd.edu.ph/wp-content/uploads/2026/05/CSEN-figure-1024x796.png 1024w, https://science.upd.edu.ph/wp-content/uploads/2026/05/CSEN-figure-768x597.png 768w" sizes="(max-width: 1152px) 100vw, 1152px" />											<figcaption class="widget-image-caption wp-caption-text">Pinaghahambing ng CSEN analysis ang dalawang reaction networks na pareho o magkatulad ang sistema sa pamamagitan ng pagtuon sa kanilang mga karaniwang species, tulad ng mga protein o kemikal, upang matukoy ang mga pagkakatulad at pagkakaiba. (Photo credit: Hernandez et al., 2024)</figcaption>
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				<p><span style="font-weight: 400;">Binuo ni Dr. Bryan Hernandez ng University of the Philippines – Diliman College of Science Institute of Mathematics (UPD-CS IM), kasama sina Patrick Vincent Lubenia at Dr. Eduardo Mendoza ng Center for Natural Science and Environmental Research, De La Salle University, ang Common Species Embedded Networks (CSEN) analysis.</span></p><p> </p><p><span style="font-weight: 400;">Pinaghahambing ng CSEN analysis ang dalawang reaction networks na pareho o magkatulad ang sistema sa pamamagitan ng pagtuon sa kanilang mga karaniwang species, tulad ng mga protein o kemikal, upang matukoy ang mga pagkakatulad at pagkakaiba.</span></p><p> </p><p><span style="font-weight: 400;">&#8220;Gumagana ang method sa pamamagitan ng unang paghihiwalay sa mga network na &#8216;naka-embed&#8217; sa loob ng mga modelo na kinasasangkutan lamang ng mga karaniwang species. Para sa mga reaksyon na hindi magkapareho, sinusuri ng method ang mga &#8216;transformation&#8217;—mga mathematical link na maaaring magpaliwanag kung paano maaaring magdulot ng equivalence ang isang set ng reaksyon sa pagitan ng mga system na may underlying embedded networks,&#8221; paliwanag ni Dr. Hernandez.</span></p><p> </p><p><span style="font-weight: 400;">Inihambing ng kanilang grupo ang mga kasalukuyang reaction network na nauugnay sa mga Wnt signaling model na kanilang natukoy, kasama ang mga iyon nina Lee, Schmitz, MacLean, at Feinberg. Sa pamamagitan ng CSEN analysis, nalaman ng mga mathematician na ang ilang umiiral na mga modelo ay lubos na magkatulad dahil ang kanilang mga embedded network ay konektado sa isa’t isa sa pamamagitan ng mga partikular na transformation. Sa kabilang banda, maaari ring mabunyag ng analysis kung walang maihahambing na relasyon ang umiiral sa mga modelo dahil sa kawalan ng naturang transformation.</span></p><p> </p><p><span style="font-weight: 400;">Ibinahagi ni Dr. Hernandez ang inspirasyon ng grupo sa likod ng paglikha ng CSEN analysis. &#8220;Sa larangan ng systems biology, madalas na nagmumungkahi ang iba&#8217;t ibang mananaliksik ng iba&#8217;t ibang mga reaction network upang ilarawan ang iisang biological process. Sa kasaysayan, mahirap ding paghambingin ang mga modelong ito dahil madalas silang ituring bilang ganap na magkahiwalay na mga entity, na gumagamit ng iba&#8217;t ibang hanay ng mga variable at reaction.&#8221;</span></p><p> </p><p><span style="font-weight: 400;">Tinutugunan ng CSEN analysis ang kahirapang ito sa pamamagitan ng pagbibigay-diin sa dalawang pangunahing haligi: network embedding, kung saan sinasala ang mga complex network para ituon lang sa mga species na makikita sa pagitan ng mga model; at mga structural comparison, kung saan sinusuri ang mga embedded network upang matukoy kung ang isang model ay isang mas kumplikadong bersyon ng isa pa o kung ang mga ito ay &#8220;halos katumbas&#8221; sa pamamagitan ng mga mathematical transformation.</span></p><p> </p><p><span style="font-weight: 400;">&#8220;Madalas napaghihiwalay ang mga modelo ng mga traditional approach batay sa mga specific property, tulad ng kung mayroon silang isang long-term state (mono-stationarity) o multiple long term states (multi-stationarity). Iba ang CSEN dahil tinitingnan nito ang underlying structure at dynamic equivalence,&#8221; dagdag ni Dr. Hernandez.</span></p><p> </p><p><span style="font-weight: 400;">Naging insightful ang CSEN analysis sa Wnt signaling, na nagpapakitang ang ilang models—na noong una ay itinuturing na naiiba dahil sa kanilang mga stability property—ay talagang halos magkapareho sa istruktura.</span></p><p> </p><p><span style="font-weight: 400;">Ayon kay Dr. Hernandez, isang pangkalahatang mathematical tool ang CSEN analysis na maaaring ilapat sa mga modelo para sa mga system maliban pa sa Wnt signaling. &#8220;Habang ipinakita namin ang paggamit nito sa Wnt signaling, maaari itong ilapat sa anumang system na kinakatawan ng mga reaction network. Kabilang dito ang iba pang biological pathway, gaya ng insulin signaling o metabolism, pati na rin ang mga potential non-biological network gaya ng mga chemical engineering process o ecological model.&#8221;</span></p><p> </p><p><span style="font-weight: 400;">Maaaring maging mahalaga ang CSEN analysis sa pagpino ng mga model sa biological at chemical systems sa pamamagitan ng pagtukoy kung aling mga bahagi ng isang modelo—o kung aling mga modelo—ang natatangi at alin ang redundant. Maaaring bigyan ng pansin ng analysis na ito ang mga robust target: kung maraming mga modelo, sa kabila ng kanilang mga pagkakaiba, ay nagkakaisa sa iisang interaction na nagdudulot ng isang uri ng sakit, ang interaction na ito ay nagiging isang mas maaasahan at robust na therapeutic target.</span></p><p> </p><p><span style="font-weight: 400;">Ang kanilang pagsasaliksik, “Embedding-based comparison of reaction networks of Wnt signaling,&#8221; ay kasama sa </span><i><span style="font-weight: 400;">MATCH Communications in Mathematical and in Computer Chemistry</span></i><span style="font-weight: 400;">, isang open-access na journal na naglalathala ng mga orihinal na pananaliksik pati na rin ang mga review ukol sa chemically important mathematical results at non-routine na paggamit ng mga mathematical technique sa mga chemical problem.</span></p><p> </p><p><b>References:</b></p><p><span style="font-weight: 400;">Hernandez, B. S., Lubenia, P. V., &amp; Mendoza, E. R. (2024). Embedding-based comparison of reaction networks of Wnt signaling. </span><i><span style="font-weight: 400;">MATCH Communications in Mathematical and in Computer Chemistry</span></i><span style="font-weight: 400;">, </span><i><span style="font-weight: 400;">93</span></i><span style="font-weight: 400;">(1), 235-245. </span><a href="https://doi.org/10.46793/match.93-1.223h"><span style="font-weight: 400;">https://doi.org/10.46793/match.93-1.223h</span></a></p>					</div>
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					</div><p>The post <a href="https://science.upd.edu.ph/mga-pilipinong-siyentipiko-gumawa-ng-novel-method-upang-pagbutihin-ang-mga-mathematical-model-upang-makatuklas-ng-drug-targets/">Mga Pilipinong Siyentipiko Gumawa ng Novel Method upang Pagbutihin ang mga Mathematical Model upang Makatuklas ng Drug Targets</a> first appeared on <a href="https://science.upd.edu.ph">SCIENCE - University of the Philippines Diliman</a>.</p>]]></content:encoded>
					
		
		
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		<title>Filipino Scientists Develop Novel Method to Refine Mathematical Models and Identify Drug Targets</title>
		<link>https://science.upd.edu.ph/filipino-scientists-develop-novel-method-to-refine-mathematical-models-and-identify-drug-targets/?utm_source=rss&#038;utm_medium=rss&#038;utm_campaign=filipino-scientists-develop-novel-method-to-refine-mathematical-models-and-identify-drug-targets</link>
		
		<dc:creator><![CDATA[craigs]]></dc:creator>
		<pubDate>Fri, 29 May 2026 05:05:04 +0000</pubDate>
				<category><![CDATA[Latest News]]></category>
		<guid isPermaLink="false">https://science.upd.edu.ph/?p=19671</guid>

					<description><![CDATA[<p>Biological processes like the Wnt signaling pathway—which regulates crucial development and helps keep the body’s tissues functioning normally and in balance—are often described by scientists using mathematical maps called reaction networks, which serve as the foundation of mathematical models. These allow scientists to examine and compare models based on their structure alone without needing or with minimal specific parameter values. Although several Wnt models exist, they differ in how they represent the same underlying biological system. To address this, Filipino mathematicians introduced a new method to find the common ground between these different maps.</p>
<p>The post <a href="https://science.upd.edu.ph/filipino-scientists-develop-novel-method-to-refine-mathematical-models-and-identify-drug-targets/">Filipino Scientists Develop Novel Method to Refine Mathematical Models and Identify Drug Targets</a> first appeared on <a href="https://science.upd.edu.ph">SCIENCE - University of the Philippines Diliman</a>.</p>]]></description>
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			<h2 class="elementor-heading-title elementor-size-default">Filipino Scientists Develop Novel Method to Refine Mathematical Models and Identify Drug Targets</h2>		</div>
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			<h2 class="elementor-heading-title elementor-size-default">Published: May 29, 2026 <br>
By: Eunice Jean C. Patron </h2>		</div>
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			<h2 class="elementor-heading-title elementor-size-default">Biological processes like the Wnt signaling pathway—which regulates crucial development and helps keep the body’s tissues functioning normally and in balance—are often described by scientists using mathematical maps called reaction networks, which serve as the foundation of mathematical models. These allow scientists to examine and compare models based on their structure alone without needing or with minimal specific parameter values. Although several Wnt models exist, they differ in how they represent the same underlying biological system. To address this, Filipino mathematicians introduced a new method to find the common ground between these different maps.
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										<img width="1152" height="896" src="https://science.upd.edu.ph/wp-content/uploads/2026/05/CSEN-figure.png" class="attachment-full size-full wp-image-19673" alt="" srcset="https://science.upd.edu.ph/wp-content/uploads/2026/05/CSEN-figure.png 1152w, https://science.upd.edu.ph/wp-content/uploads/2026/05/CSEN-figure-300x233.png 300w, https://science.upd.edu.ph/wp-content/uploads/2026/05/CSEN-figure-1024x796.png 1024w, https://science.upd.edu.ph/wp-content/uploads/2026/05/CSEN-figure-768x597.png 768w" sizes="(max-width: 1152px) 100vw, 1152px" />											<figcaption class="widget-image-caption wp-caption-text">The CSEN analysis compares two reaction networks by focusing on their common species, such as proteins or chemicals, to identify similarities and differences. (Photo credit: Hernandez et al., 2024)</figcaption>
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				<p><span style="font-weight: 400;">Dr. Bryan Hernandez of the University of the Philippines – Diliman College of Science’s Institute of Mathematics (UPD-CS IM), along with Patrick Vincent Lubenia and Dr. Eduardo Mendoza of the Center for Natural Science and Environmental Research, De La Salle University, developed the Common Species Embedded Networks (CSEN) analysis.</span></p><p> </p><p><span style="font-weight: 400;">The CSEN analysis compares two reaction networks of the same or similar systems by focusing on their common species, such as proteins or chemicals, to identify similarities and differences.</span></p><p> </p><p><span style="font-weight: 400;">“The method works by first isolating the networks ‘embedded’ within the models that involve only the common species. For the reactions that are not identical, the method checks for ‘transformations’—mathematical links that can explain how one reaction set might induce equivalence between the systems with the underlying embedded networks,” Dr. Hernandez explained.</span></p><p> </p><p><span style="font-weight: 400;">Their group compared existing reaction networks associated with Wnt signaling models they had identified, including those by Lee, Schmitz, MacLean, and Feinberg. Through the CSEN analysis, the mathematicians found that some existing models are strongly similar because their embedded networks are connected through specific transformations. Conversely, the analysis can also reveal when no comparable relationship exists due to the absence of such transformations.</span></p><p> </p><p><span style="font-weight: 400;">Dr. Hernandez shared the team’s inspiration behind creating the CSEN analysis. “In the field of systems biology, different researchers often propose different reaction networks to describe the same biological process. Historically, it has also been difficult to compare these models because they are often treated as entirely separate entities, utilizing different sets of variables and reactions.”</span></p><p> </p><p><span style="font-weight: 400;">The CSEN analysis addresses this difficulty by emphasizing two key pillars: network embedding, which narrows complex networks to focus only on the species shared between models; and structural comparisons, in which the embedded networks are analyzed to determine whether one model is a more complex version of another or if they are “proximately equivalent” through mathematical transformations.</span></p><p><span style="font-weight: 400;">“Traditional approaches often discriminate between models based on specific properties, such as whether they have one long-term state (mono-stationarity) or the capacity for multiple long-term</span> <span style="font-weight: 400;">states (multi-stationarity). CSEN is different because it looks at the underlying structure and dynamical equivalence,” Dr. Hernandez added.</span></p><p> </p><p><span style="font-weight: 400;">The CSEN analysis was particularly insightful for Wnt signaling, revealing that certain models—previously thought to differ fundamentally due to their stability properties—are actually structurally very similar.</span></p><p> </p><p><span style="font-weight: 400;">According to Dr. Hernandez, the CSEN analysis is a general mathematical tool that can be applied to models in systems beyond Wnt signaling. “While we demonstrated its use with Wnt signaling, it can be applied to any system represented by reaction networks. This includes other biological pathways, such as insulin signaling or metabolism, as well as potentially non-biological networks such as chemical engineering processes or ecological models.”</span></p><p> </p><p><span style="font-weight: 400;">The CSEN analysis can be vital in refining models in biological and chemical systems by identifying which parts of a model—or which models—are unique and which are redundant. This method can highlight robust targets: if many models, despite their differences, agree that a specific interaction drives a disease, that interaction becomes a more reliable and robust therapeutic target.</span></p><p> </p><p><span style="font-weight: 400;">Their research, “Embedding-based comparison of reaction networks of Wnt signaling,” is included in </span><i><span style="font-weight: 400;">MATCH Communications in Mathematical and in Computer Chemistry</span></i><span style="font-weight: 400;">, an open-access journal that publishes papers of original research as well as reviews on chemically important mathematical results and non-routine applications of mathematical techniques to chemical problems.</span></p><p> </p><p><b>References:</b></p><p><span style="font-weight: 400;">Hernandez, B. S., Lubenia, P. V., &amp; Mendoza, E. R. (2024). Embedding-based comparison of reaction networks of Wnt signaling. </span><i><span style="font-weight: 400;">MATCH Communications in Mathematical and in Computer Chemistry</span></i><span style="font-weight: 400;">, </span><i><span style="font-weight: 400;">93</span></i><span style="font-weight: 400;">(1), 235-245. </span><a href="https://doi.org/10.46793/match.93-1.223h"><span style="font-weight: 400;">https://doi.org/10.46793/match.93-1.223h</span></a></p>					</div>
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				<p> </p><p><b style="color: var( --e-global-color-text ); font-family: var( --e-global-typography-secondary-font-family ), Sans-serif; font-size: var( --e-global-typography-secondary-font-size ); letter-spacing: var( --e-global-typography-secondary-letter-spacing ); background-color: var(--global--color-background);"><i>For interview requests and other concerns, please contact </i></b><a style="font-family: var( --e-global-typography-secondary-font-family ), Sans-serif; font-size: var( --e-global-typography-secondary-font-size ); letter-spacing: var( --e-global-typography-secondary-letter-spacing );" href="mailto:media@science.upd.edu.ph"><b><i>media@science.upd.edu.ph</i></b></a><i style="color: var( --e-global-color-text ); font-family: var( --e-global-typography-secondary-font-family ), Sans-serif; font-size: var( --e-global-typography-secondary-font-size ); font-weight: var( --e-global-typography-secondary-font-weight ); letter-spacing: var( --e-global-typography-secondary-letter-spacing ); background-color: var(--global--color-background);">.</i></p>					</div>
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					</div><p>The post <a href="https://science.upd.edu.ph/filipino-scientists-develop-novel-method-to-refine-mathematical-models-and-identify-drug-targets/">Filipino Scientists Develop Novel Method to Refine Mathematical Models and Identify Drug Targets</a> first appeared on <a href="https://science.upd.edu.ph">SCIENCE - University of the Philippines Diliman</a>.</p>]]></content:encoded>
					
		
		
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		<title>UPD Chemists nag-develop ng AI Tool Laban sa Drug-Resistant Bacteria</title>
		<link>https://science.upd.edu.ph/upd-chemists-nag-develop-ng-ai-tool-laban-sa-drug-resistant-bacteria/?utm_source=rss&#038;utm_medium=rss&#038;utm_campaign=upd-chemists-nag-develop-ng-ai-tool-laban-sa-drug-resistant-bacteria</link>
		
		<dc:creator><![CDATA[craigs]]></dc:creator>
		<pubDate>Tue, 12 May 2026 09:07:02 +0000</pubDate>
				<category><![CDATA[Latest News]]></category>
		<guid isPermaLink="false">https://science.upd.edu.ph/?p=19636</guid>

					<description><![CDATA[<p>Habang patuloy ang paghina o pagkawalang bisa ng mga tradisyunal na antibiotic sanhi ng antimicrobial resistance (AMR), ay lalong nagiging mahalaga ang paghahanap ng mga bagong gamot. Isa sa mga pinakapromising na solusyon ay ang antimicrobial peptides (AMPs), na isang klase ng mga compound na kayang pumatay ng bacteria. Upang mapabilis ang proseso ng pagtuklas ng AMPs, bumuo sila Remmer Salas, Dr. Portia Mahal Sabido, at Dr. Ricky Nellas ng University of the Philippines Diliman – College of Science (UPD-CS) ng isang AI tool.</p>
<p>The post <a href="https://science.upd.edu.ph/upd-chemists-nag-develop-ng-ai-tool-laban-sa-drug-resistant-bacteria/">UPD Chemists nag-develop ng AI Tool Laban sa Drug-Resistant Bacteria</a> first appeared on <a href="https://science.upd.edu.ph">SCIENCE - University of the Philippines Diliman</a>.</p>]]></description>
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			<h2 class="elementor-heading-title elementor-size-default">UPD Chemists nag-develop ng AI Tool Laban sa Drug-Resistant Bacteria</h2>		</div>
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			<h2 class="elementor-heading-title elementor-size-default">Published: May 12, 2026 <br>
By: Eunice Jean C. Patron  <br>
Translated by: Dr. Eizadora T. Yu</h2>		</div>
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										<img width="1817" height="660" src="https://science.upd.edu.ph/wp-content/uploads/2026/05/iscape_grabs.png" class="attachment-full size-full wp-image-19632" alt="" srcset="https://science.upd.edu.ph/wp-content/uploads/2026/05/iscape_grabs.png 1817w, https://science.upd.edu.ph/wp-content/uploads/2026/05/iscape_grabs-300x109.png 300w, https://science.upd.edu.ph/wp-content/uploads/2026/05/iscape_grabs-1024x372.png 1024w, https://science.upd.edu.ph/wp-content/uploads/2026/05/iscape_grabs-768x279.png 768w, https://science.upd.edu.ph/wp-content/uploads/2026/05/iscape_grabs-1536x558.png 1536w, https://science.upd.edu.ph/wp-content/uploads/2026/05/iscape_grabs-1568x570.png 1568w" sizes="(max-width: 1817px) 100vw, 1817px" />											<figcaption class="widget-image-caption wp-caption-text">Ang ISCAPE ay isang AI-powered tool na tumutulong na mag-predict kung ang isang peptide ay may kakayahang pumatay o pumigil sa  pagdami ng E. coli. (Photo credit: Salas et. al., 2026)</figcaption>
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				<p><span style="font-weight: 400;">Habang patuloy ang paghina o pagkawalang bisa ng mga tradisyunal na antibiotic sanhi ng antimicrobial resistance (AMR), ay lalong nagiging mahalaga ang paghahanap ng mga bagong gamot. Isa sa mga pinakapromising na solusyon ay ang antimicrobial peptides (AMPs), na isang klase ng mga compound na kayang pumatay ng bacteria. Upang mapabilis ang proseso ng pagtuklas ng AMPs, bumuo sila Remmer Salas, Dr. Portia Mahal Sabido, at Dr. Ricky Nellas ng University of the Philippines Diliman – College of Science (UPD-CS) ng isang AI tool.</span></p><p> </p><p><span style="font-weight: 400;">Ang ISCAPE</span> <span style="font-weight: 400;">(Interpretable Support Vector Classifier of Antibacterial Activity of Peptides against </span><i><span style="font-weight: 400;">Escherichia coli</span></i><span style="font-weight: 400;">) ay isang AI-powered tool na tumutulong na mag-predict kung ang isang peptide ay may kakayahang pumatay o pumigil sa pagdami ng </span><i><span style="font-weight: 400;">E. coli</span></i><span style="font-weight: 400;">. Kailangan lamang ng system na ito ng Simplified Molecular-Input Line-Entry System (SMILES) string bilang input, bagay na magpapadali sa mga researcher na suriin ang mga kandidatong molecule</span><span style="font-weight: 400;">.</span></p><p> </p><p><span style="font-weight: 400;">“Ayon sa tradisyunal na paraan, ang pagtuklas ng antibacterial peptides ay nangangailangan ng paggawa o pag-synthesize ng maraming kandidato at pagsubok sa mga ito isa-isa. Matagal ang prosesong ito,” sabi ni Salas. “Gumamit kami ng AI upang matuto mula sa umiiral na datos at matukoy ang mga pattern na nagkakaiba sa mga aktibo at hindi aktibong peptide</span><span style="font-weight: 400;">.”</span></p><p> </p><p><span style="font-weight: 400;">Bukod-tangi din sa mga AI tools ang abilidad ng ISCAPE na tukuyin kung aling mga </span><i><span style="font-weight: 400;">molecular feature</span></i><span style="font-weight: 400;"> ang nagpapabisa sa isang peptide. Ayon kay Salas, nakatutulong ito upang makatipid ng oras at resources ang mga researcher. Nababawasan nito ang trial-and-error experiments at nagbibigay-daan upang mas mahusay na makapagdisenyo ng peptide.</span></p><p> </p><p><span style="font-weight: 400;">“Tumutulong ang ISCAPE sa laban sa antimicrobial resistance sa pamamagitan ng pagpapabilis ng early-stage screening gamit ang data-driven peptide design,” dagdag pa ni Salas. “Hindi nito pinapalitan ang laboratory experiments, ngunit ginagawa nitong mas episyente ang discovery process at tinutulungan ang mga researcher na magpokus sa mga pinakapromising na kandidato.”</span></p><p> </p><p><span style="font-weight: 400;">Maaaring ding magamit ang AI-powered model  laban sa ibang bacteria bukod sa E. coli. Gayunpaman, kailangan muna itong sanayin muli gamit ang mataas na kalidad na datasets na partikular sa bacterial strains na nais pag-aralan. Maaari ring gamitin ang ISCAPE approach upang hulaan o mag-predict ng activity ng iba pang bioactive peptides.</span></p><p> </p><p><span style="font-weight: 400;">“Ang paggamit ng ISCAPE para sa ibang biological targets ay nangangailangan ng maayos na </span><i><span style="font-weight: 400;">curated datasets</span></i><span style="font-weight: 400;"> na may experimentally validated activity,” dagdag ni Salas. “Pagkatapos nito, kailangang sanayin muli ang model gamit ang molecular features na natukoy naming pinakamainam para sa peptides.”</span></p><p> </p><p><span style="font-weight: 400;">Umaasa ang grupo na makatutulong ang ISCAPE upang mas mahusay at mas mabilis na makapagdisenyo ang mga researcher ng antibacterial peptides at makatulong sa pandaigdigang laban kontra AMR.</span></p><p> </p><p><span style="font-weight: 400;">Bukas sa publiko ang ISCAPE para magamit ng ibang siyentista. Maaaring ma-access ang web server nito sa Hugging Face Spaces. Available din sa GitHub ang training data at code para sa large-scale prediction.</span></p><p> </p><p><span style="font-weight: 400;">Ang research paper na pinamagatang “Interpretable support vector classifier for reliable prediction of antibacterial activity of modified peptides against </span><i><span style="font-weight: 400;">Escherichia coli</span></i><span style="font-weight: 400;">” ay nailathala sa </span><i><span style="font-weight: 400;">Journal of Molecular Graphics and Modelling</span></i><span style="font-weight: 400;">. Ang internasyonal na publikasyong ito ay naglalaman ng mga papel tungkol sa paggamit ng computer sa teoretikal na pag-aaral ng molecular structure, function, interaction, at design. Saklaw nito ang lahat ng aspeto ng molecular modeling at computational chemistry.</span></p><p> </p><p><b>References:</b></p><p><span style="font-weight: 400;">Salas, R. L., Sabido, P. M., &amp; Nellas, R. B. (2026). Interpretable support vector classifier for reliable prediction of antibacterial activity of modified peptides against </span><i><span style="font-weight: 400;">Escherichia coli</span></i><span style="font-weight: 400;">. </span><i><span style="font-weight: 400;">Journal of Molecular Graphics and Modelling</span></i><span style="font-weight: 400;">, </span><i><span style="font-weight: 400;">142</span></i><span style="font-weight: 400;">, 109188. </span><a href="https://doi.org/10.1016/j.jmgm.2025.109188"><span style="font-weight: 400;">https://doi.org/10.1016/j.jmgm.2025.109188</span></a></p>					</div>
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				<p> </p><p><b style="color: var( --e-global-color-text ); font-family: var( --e-global-typography-secondary-font-family ), Sans-serif; font-size: var( --e-global-typography-secondary-font-size ); letter-spacing: var( --e-global-typography-secondary-letter-spacing ); background-color: var(--global--color-background);"><i>For interview requests and other concerns, please contact </i></b><a style="font-family: var( --e-global-typography-secondary-font-family ), Sans-serif; font-size: var( --e-global-typography-secondary-font-size ); letter-spacing: var( --e-global-typography-secondary-letter-spacing );" href="mailto:media@science.upd.edu.ph"><b><i>media@science.upd.edu.ph</i></b></a><i style="color: var( --e-global-color-text ); font-family: var( --e-global-typography-secondary-font-family ), Sans-serif; font-size: var( --e-global-typography-secondary-font-size ); font-weight: var( --e-global-typography-secondary-font-weight ); letter-spacing: var( --e-global-typography-secondary-letter-spacing ); background-color: var(--global--color-background);">.</i></p>					</div>
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					</div><p>The post <a href="https://science.upd.edu.ph/upd-chemists-nag-develop-ng-ai-tool-laban-sa-drug-resistant-bacteria/">UPD Chemists nag-develop ng AI Tool Laban sa Drug-Resistant Bacteria</a> first appeared on <a href="https://science.upd.edu.ph">SCIENCE - University of the Philippines Diliman</a>.</p>]]></content:encoded>
					
		
		
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		<title>UPD Chemists Create AI Tool to Predict Antibacterial Peptides</title>
		<link>https://science.upd.edu.ph/upd-chemists-create-ai-tool-to-predict-antibacterial-peptides/?utm_source=rss&#038;utm_medium=rss&#038;utm_campaign=upd-chemists-create-ai-tool-to-predict-antibacterial-peptides</link>
		
		<dc:creator><![CDATA[craigs]]></dc:creator>
		<pubDate>Tue, 12 May 2026 08:53:01 +0000</pubDate>
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					<description><![CDATA[<p>As antimicrobial resistance (AMR) continues to make traditional antibiotics less effective worldwide, the search for new antibacterial treatments has become increasingly urgent. One promising solution is antimicrobial peptides (AMPs), small molecules that can kill bacteria. To help accelerate their discovery, researchers at the University of the Philippines Diliman – College of Science (UPD-CS) have developed an AI tool designed to accelerate the discovery of new antibacterial peptides.</p>
<p>The post <a href="https://science.upd.edu.ph/upd-chemists-create-ai-tool-to-predict-antibacterial-peptides/">UPD Chemists Create AI Tool to Predict Antibacterial Peptides</a> first appeared on <a href="https://science.upd.edu.ph">SCIENCE - University of the Philippines Diliman</a>.</p>]]></description>
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			<h2 class="elementor-heading-title elementor-size-default">UPD Chemists Create AI Tool to Predict Antibacterial Peptides
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			<h2 class="elementor-heading-title elementor-size-default">Published: May 12, 2026 <br>
By: Eunice Jean C. Patron </h2>		</div>
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										<img width="1817" height="660" src="https://science.upd.edu.ph/wp-content/uploads/2026/05/iscape_grabs.png" class="attachment-full size-full wp-image-19632" alt="" srcset="https://science.upd.edu.ph/wp-content/uploads/2026/05/iscape_grabs.png 1817w, https://science.upd.edu.ph/wp-content/uploads/2026/05/iscape_grabs-300x109.png 300w, https://science.upd.edu.ph/wp-content/uploads/2026/05/iscape_grabs-1024x372.png 1024w, https://science.upd.edu.ph/wp-content/uploads/2026/05/iscape_grabs-768x279.png 768w, https://science.upd.edu.ph/wp-content/uploads/2026/05/iscape_grabs-1536x558.png 1536w, https://science.upd.edu.ph/wp-content/uploads/2026/05/iscape_grabs-1568x570.png 1568w" sizes="(max-width: 1817px) 100vw, 1817px" />											<figcaption class="widget-image-caption wp-caption-text">ISCAPE helps experimentalists predict whether a peptide can kill or inhibit the growth of the bacterium Escherichia coli. (Photo credit: Salas et. al., 2026)</figcaption>
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				<p><span style="font-weight: 400;">As antimicrobial resistance (AMR) continues to make traditional antibiotics less effective worldwide, the search for new antibacterial treatments has become increasingly urgent. One promising solution is antimicrobial peptides (AMPs), small molecules that can kill bacteria. To help accelerate their discovery, researchers at the University of the Philippines Diliman – College of Science (UPD-CS) have developed an AI tool designed to accelerate the discovery of new antibacterial peptides.</span></p><p> </p><p><span style="font-weight: 400;">Remmer Salas, Dr. Portia Mahal Sabido, and Dr. Ricky Nellas of the UPD-CS Institute of Chemistry (IC) developed ISCAPE (Interpretable Support Vector Classifier of Antibacterial Activity of Peptides against </span><i><span style="font-weight: 400;">Escherichia coli</span></i><span style="font-weight: 400;">). It is an AI-powered tool that helps experimentalists predict whether a peptide can kill or inhibit the growth of </span><i><span style="font-weight: 400;">E. coli</span></i><span style="font-weight: 400;">. The system requires only a Simplified Molecular-Input Line-Entry System (SMILES) string as input, making it simple for researchers to evaluate candidate molecules.</span></p><p> </p><p><span style="font-weight: 400;">“Traditionally, discovering antibacterial peptides means synthesizing many candidates and testing them one by one. This process is time-consuming,” said Salas. “We used AI to learn from existing data and identify patterns that distinguish active peptides from inactive ones.”</span></p><p> </p><p><span style="font-weight: 400;">Unlike many AI tools, ISCAPE also shows which molecular features make a peptide effective. He noted that this helps researchers save time and resources. It reduces trial-and-error experiments and allows them to design better peptides more efficiently.</span></p><p> </p><p><span style="font-weight: 400;">“ISCAPE helps address antimicrobial resistance by accelerating early-stage screening through data-driven peptide design,” Salas further explained. “It doesn’t replace laboratory experiments, but it makes discovery more efficient and helps researchers focus on the most promising candidates.”</span></p><p> </p><p><span style="font-weight: 400;">The AI-powered model can be adapted to predict activity against bacteria other than </span><i><span style="font-weight: 400;">E. coli</span></i><span style="font-weight: 400;">. However, it would need to be retrained using high-quality datasets specific to the bacterial strains of interest. The ISCAPE approach could also be applied to predict the activity of other bioactive peptides. </span></p><p> </p><p><span style="font-weight: 400;">“Applying ISCAPE to other biological targets requires well-curated datasets with experimentally validated activity,” Salas added. “The model must then be retrained using the molecular features we identified as optimal for peptides.”</span></p><p> </p><p><span style="font-weight: 400;">The team hopes the tool will help researchers design better antibacterial peptides more efficiently and contribute to the global fight against AMR.</span></p><p> </p><p><span style="font-weight: 400;">ISCAPE is publicly available for other scientists. The web server can be accessed through </span><a href="https://huggingface.co/spaces/rlsalas/iscape"><span style="font-weight: 400;">Hugging Face Spaces</span></a><span style="font-weight: 400;">. The training data and code for large-scale prediction are available on </span><a href="https://github.com/mersalas/ISCAPE"><span style="font-weight: 400;">GitHub</span></a><span style="font-weight: 400;">.</span></p><p> </p><p><span style="font-weight: 400;">The chemists’ research paper, titled “Interpretable support vector classifier for reliable prediction of antibacterial activity of modified peptides against </span><i><span style="font-weight: 400;">Escherichia coli</span></i><span style="font-weight: 400;">,” was included in the </span><i><span style="font-weight: 400;">Journal of Molecular Graphics and Modelling</span></i><span style="font-weight: 400;">. This international publication features papers on the use of computers in theoretical investigations of molecular structure, function, interaction, and design. It covers all aspects of molecular modeling and computational chemistry.</span></p><p> </p><p><b>References:</b></p><p><span style="font-weight: 400;">Salas, R. L., Sabido, P. M., &amp; Nellas, R. B. (2026). Interpretable support vector classifier for reliable prediction of antibacterial activity of modified peptides against </span><i><span style="font-weight: 400;">Escherichia coli</span></i><span style="font-weight: 400;">. </span><i><span style="font-weight: 400;">Journal of Molecular Graphics and Modelling</span></i><span style="font-weight: 400;">, </span><i><span style="font-weight: 400;">142</span></i><span style="font-weight: 400;">, 109188. </span><a href="https://doi.org/10.1016/j.jmgm.2025.109188"><span style="font-weight: 400;">https://doi.org/10.1016/j.jmgm.2025.109188</span></a></p>					</div>
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				<p> </p><p><b style="color: var( --e-global-color-text ); font-family: var( --e-global-typography-secondary-font-family ), Sans-serif; font-size: var( --e-global-typography-secondary-font-size ); letter-spacing: var( --e-global-typography-secondary-letter-spacing ); background-color: var(--global--color-background);"><i>For interview requests and other concerns, please contact </i></b><a style="font-family: var( --e-global-typography-secondary-font-family ), Sans-serif; font-size: var( --e-global-typography-secondary-font-size ); letter-spacing: var( --e-global-typography-secondary-letter-spacing );" href="mailto:media@science.upd.edu.ph"><b><i>media@science.upd.edu.ph</i></b></a><i style="color: var( --e-global-color-text ); font-family: var( --e-global-typography-secondary-font-family ), Sans-serif; font-size: var( --e-global-typography-secondary-font-size ); font-weight: var( --e-global-typography-secondary-font-weight ); letter-spacing: var( --e-global-typography-secondary-letter-spacing ); background-color: var(--global--color-background);">.</i></p>					</div>
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					</div><p>The post <a href="https://science.upd.edu.ph/upd-chemists-create-ai-tool-to-predict-antibacterial-peptides/">UPD Chemists Create AI Tool to Predict Antibacterial Peptides</a> first appeared on <a href="https://science.upd.edu.ph">SCIENCE - University of the Philippines Diliman</a>.</p>]]></content:encoded>
					
		
		
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		<title>BATCH 2 of Graduate Program Applications Open for 1st Semester AY 2026-2027</title>
		<link>https://science.upd.edu.ph/graduation-program-applications-open-for-1st-semester-ay-2026-2027/?utm_source=rss&#038;utm_medium=rss&#038;utm_campaign=graduation-program-applications-open-for-1st-semester-ay-2026-2027</link>
		
		<dc:creator><![CDATA[craigs]]></dc:creator>
		<pubDate>Tue, 12 May 2026 06:57:28 +0000</pubDate>
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					<description><![CDATA[<p>BATCH 2 Applications to College of Science Graduate Programs for the 1st Semester of AY 2026-2027 are now open. Deadline for applications is on July 08, 2026.</p>
<p>The post <a href="https://science.upd.edu.ph/graduation-program-applications-open-for-1st-semester-ay-2026-2027/">BATCH 2 of Graduate Program Applications Open for 1st Semester AY 2026-2027</a> first appeared on <a href="https://science.upd.edu.ph">SCIENCE - University of the Philippines Diliman</a>.</p>]]></description>
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			<h2 class="elementor-heading-title elementor-size-default">BATCH 2 Graduate Program Applications Open for 1st Semester AY 2026-2027</h2>		</div>
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				<div dir="auto"><div dir="auto"><div dir="auto"><div dir="auto">BATCH 2 of Applications to College of Science Graduate Programs for the 1st Semester of AY 2026-2027 are now open. Deadline for applications is now on <strong>July 08, 2026.</strong></div></div></div></div><div dir="auto"> </div><div dir="auto"><strong>HOW TO APPLY:</strong></div><div dir="auto"> </div><div dir="auto"><strong>Via College of Science <a href="https://online.science.upd.edu.ph/CSCentralizedPortal/Main/application-to-graduate-programs.php">Online Document Portal (ODP) </a></strong></div><ul><li dir="auto"><strong>Data Science Program</strong></li><li dir="auto"><strong>Institute of Environmental Science and Meteorology</strong></li><li dir="auto"><strong>National Institute of Geological Sciences</strong></li><li dir="auto"><strong>National Institute of Molecular Biology and Biotechnology</strong></li></ul><div dir="auto"> </div><div dir="auto"><strong>Via Google Form &#8211; <a href="https://bit.ly/CSApplicationGradProgram-1st-26-27"><em>bit.ly/CSApplicationGradProgram-1st-26-27</em></a></strong></div><ul><li dir="auto">Institute of Biology</li><li dir="auto">Institute of Chemistry</li><li dir="auto">Institute of Mathematics</li><li dir="auto">Marine Science Institute</li><li dir="auto">Materials Science Engineering Program</li><li dir="auto">National Institute of Physics</li></ul>					</div>
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												<img width="620" height="775" src="https://science.upd.edu.ph/wp-content/uploads/2026/05/OADAA-Graduate-Program-Application-2026-BATCH-2-Pub-02-1-819x1024.png" class="attachment-large size-large wp-image-19664" alt="" srcset="https://science.upd.edu.ph/wp-content/uploads/2026/05/OADAA-Graduate-Program-Application-2026-BATCH-2-Pub-02-1-819x1024.png 819w, https://science.upd.edu.ph/wp-content/uploads/2026/05/OADAA-Graduate-Program-Application-2026-BATCH-2-Pub-02-1-240x300.png 240w, https://science.upd.edu.ph/wp-content/uploads/2026/05/OADAA-Graduate-Program-Application-2026-BATCH-2-Pub-02-1-768x960.png 768w, https://science.upd.edu.ph/wp-content/uploads/2026/05/OADAA-Graduate-Program-Application-2026-BATCH-2-Pub-02-1-1229x1536.png 1229w, https://science.upd.edu.ph/wp-content/uploads/2026/05/OADAA-Graduate-Program-Application-2026-BATCH-2-Pub-02-1-1638x2048.png 1638w, https://science.upd.edu.ph/wp-content/uploads/2026/05/OADAA-Graduate-Program-Application-2026-BATCH-2-Pub-02-1-1568x1960.png 1568w, https://science.upd.edu.ph/wp-content/uploads/2026/05/OADAA-Graduate-Program-Application-2026-BATCH-2-Pub-02-1.png 1800w" sizes="(max-width: 620px) 100vw, 620px" />														</div>
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					</div><p>The post <a href="https://science.upd.edu.ph/graduation-program-applications-open-for-1st-semester-ay-2026-2027/">BATCH 2 of Graduate Program Applications Open for 1st Semester AY 2026-2027</a> first appeared on <a href="https://science.upd.edu.ph">SCIENCE - University of the Philippines Diliman</a>.</p>]]></content:encoded>
					
		
		
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		<title>Halaman sa Tabing-Ilog: Mahalaga para sa Konserbasyon￼</title>
		<link>https://science.upd.edu.ph/halaman-sa-tabing-ilog-mahalaga-para-sa-konserbasyon%ef%bf%bc/?utm_source=rss&#038;utm_medium=rss&#038;utm_campaign=halaman-sa-tabing-ilog-mahalaga-para-sa-konserbasyon%25ef%25bf%25bc</link>
		
		<dc:creator><![CDATA[craigs]]></dc:creator>
		<pubDate>Thu, 30 Apr 2026 05:49:09 +0000</pubDate>
				<category><![CDATA[Latest News]]></category>
		<guid isPermaLink="false">https://science.upd.edu.ph/?p=19470</guid>

					<description><![CDATA[<p>Ang riparian vegetation, o mga halamang tumutubo sa pampang ng ilog, ay mahalaga sa kalusugan ng mga ecosystem ng ilog, ngunit napakasensitibo sa mga pagbabago sa daloy ng ilog, sediment at mga kaguluhan sa lupa (land disturbance).</p>
<p>The post <a href="https://science.upd.edu.ph/halaman-sa-tabing-ilog-mahalaga-para-sa-konserbasyon%ef%bf%bc/">Halaman sa Tabing-Ilog: Mahalaga para sa Konserbasyon￼</a> first appeared on <a href="https://science.upd.edu.ph">SCIENCE - University of the Philippines Diliman</a>.</p>]]></description>
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			<h2 class="elementor-heading-title elementor-size-default">Halaman sa Tabing-Ilog: Mahalaga para sa Konserbasyon 
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			<h2 class="elementor-heading-title elementor-size-default">Published: April 30, 2026 <br>
By: Eunice Jean C. Patron <br>
Translated by: Dr. Eizadora T. Yu</h2>		</div>
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				<p><span style="font-weight: 400;">Ang </span><i><span style="font-weight: 400;">riparian vegetation</span></i><span style="font-weight: 400;">, o mga halamang tumutubo sa pampang ng ilog, ay mahalaga sa kalusugan ng mga ecosystem ng ilog, ngunit napakasensitibo sa mga pagbabago sa daloy ng ilog, sediment at mga kaguluhan sa lupa (</span><i><span style="font-weight: 400;">land disturbance</span></i><span style="font-weight: 400;">).</span></p><p> </p>					</div>
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										<img width="1803" height="868" src="https://science.upd.edu.ph/wp-content/uploads/2026/04/3_View-of-the-River-Mouth_2.png" class="attachment-full size-full wp-image-19459" alt="" srcset="https://science.upd.edu.ph/wp-content/uploads/2026/04/3_View-of-the-River-Mouth_2.png 1803w, https://science.upd.edu.ph/wp-content/uploads/2026/04/3_View-of-the-River-Mouth_2-300x144.png 300w, https://science.upd.edu.ph/wp-content/uploads/2026/04/3_View-of-the-River-Mouth_2-1024x493.png 1024w, https://science.upd.edu.ph/wp-content/uploads/2026/04/3_View-of-the-River-Mouth_2-768x370.png 768w, https://science.upd.edu.ph/wp-content/uploads/2026/04/3_View-of-the-River-Mouth_2-1536x739.png 1536w, https://science.upd.edu.ph/wp-content/uploads/2026/04/3_View-of-the-River-Mouth_2-1568x755.png 1568w" sizes="(max-width: 1803px) 100vw, 1803px" />											<figcaption class="widget-image-caption wp-caption-text">Bunganga ng ilog. (Photo credit: Dr. Enrico Replan</figcaption>
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				<p><span style="font-weight: 400;">Sa mga tropikal na ilog tulad ng mga matatagpuan sa Pilipinas, kadalasan ay naiipon ang mga sediment at nagbabago ng kapaligiran, kaya’t mahalagang magsagawa ng baseline studies sa mga partikular na lugar. Ito ang motibasyon ni Dr. Enrico Replan ng University of the Philippines – Diliman College of Science’s Institute of Environmental Science and Meteorology (UPD-CS IESM) para pag aralan ang mga halamang tumutubo sa tabi ng Amnay River sa Occidental Mindoro at makita kung ano ang ugnayan ng kanilang distribusyon sa kapaligiran ng ilog.</span></p><p> </p><p><span style="font-weight: 400;">Malawak ang sakop ng pag-aaral ni Dr. Replan- mahigit na 14 na kilometro ng downstream river corridor, na sumasaklaw sa mahigit na 509 na ektarya, kasama ang mga pampang ng ilog at kalapit na halamanan na minsan ay umaabot papaloob (</span><i><span style="font-weight: 400;">inland</span></i><span style="font-weight: 400;">) sa ibang lugar. Dahil dito, maaring makita ni Dr. Replan kung paano nagbabago ang mga halamanan sa mga lugar na madaling mabaha hanggang sa mga mas terrestrial parts ng riparian landscapes.</span></p><p> </p><p><span style="font-weight: 400;">“Ang mga </span><i><span style="font-weight: 400;">riparian areas</span></i><span style="font-weight: 400;"> o mga lugar sa tabi ng ilog, ay napakahalaga dahil sa kakayanan nilang makapigil ng erosyon ng lupa, magpabuti ng kalidad ng tubig, at makapagbigay ng tirahan para sa mga hayop. Sa pagdokumento o pagtala ng mga halaman naroon, nakabuo tayo ng baseline record na maaring magamit sa pag-monitor ng mga pagbabago sa kapaligiran sa hinaharap,” aniya ni Dr. Replan.</span></p><p> </p><p><span style="font-weight: 400;">Kaunti at limitado ang siyentipikong dokumentasyon ng riparian vegetation ng Amnay River, sa kabila ng kahalagahan nito sa lokal na komunidad. “ Sa harap ng tumitinding pressure sa kapaligiran tulad ng land-use change at sedimentasyon, naramdaman kong importante na magtatag ng </span><i><span style="font-weight: 400;">baseline ecological data</span></i><span style="font-weight: 400;">,” dagdag niya, pagbibigay-diin na mahalaga ang pag-unawa sa mga halamanan sa tabi ng ilog para sa konserbasyon at </span><i><span style="font-weight: 400;">sustainable management</span></i><span style="font-weight: 400;">.</span></p><p> </p>					</div>
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										<img width="1800" height="1350" src="https://science.upd.edu.ph/wp-content/uploads/2026/04/Dr.-Replan-taking-photographs-of-plant-specimens-belonging-to-highly-specialized-plant-species-in-the-Amnay-River.jpg" class="attachment-full size-full wp-image-19460" alt="" srcset="https://science.upd.edu.ph/wp-content/uploads/2026/04/Dr.-Replan-taking-photographs-of-plant-specimens-belonging-to-highly-specialized-plant-species-in-the-Amnay-River.jpg 1800w, https://science.upd.edu.ph/wp-content/uploads/2026/04/Dr.-Replan-taking-photographs-of-plant-specimens-belonging-to-highly-specialized-plant-species-in-the-Amnay-River-300x225.jpg 300w, https://science.upd.edu.ph/wp-content/uploads/2026/04/Dr.-Replan-taking-photographs-of-plant-specimens-belonging-to-highly-specialized-plant-species-in-the-Amnay-River-1024x768.jpg 1024w, https://science.upd.edu.ph/wp-content/uploads/2026/04/Dr.-Replan-taking-photographs-of-plant-specimens-belonging-to-highly-specialized-plant-species-in-the-Amnay-River-768x576.jpg 768w, https://science.upd.edu.ph/wp-content/uploads/2026/04/Dr.-Replan-taking-photographs-of-plant-specimens-belonging-to-highly-specialized-plant-species-in-the-Amnay-River-1536x1152.jpg 1536w, https://science.upd.edu.ph/wp-content/uploads/2026/04/Dr.-Replan-taking-photographs-of-plant-specimens-belonging-to-highly-specialized-plant-species-in-the-Amnay-River-1568x1176.jpg 1568w" sizes="(max-width: 1800px) 100vw, 1800px" />											<figcaption class="widget-image-caption wp-caption-text">Kinukuhanan ni Dr. Replan ng litrato ang mga specimen ng halaman na kabilang sa mga espesyalisadong species sa Amnay River. (Photo credit: Dr. Enrico Replan)</figcaption>
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				<p><span style="font-weight: 400;">Pinapakita ng pag-aaral na ito na karamihan sa halaman ay mga herbs at disturbance-tolerant na mga halaman, lalo na mga damo (Poaceae) at </span><i><span style="font-weight: 400;">legumes</span></i><span style="font-weight: 400;"> (Fabaceae). Bihira ang mga puno at iba pang makahoy na halaman (</span><i><span style="font-weight: 400;">woody plants</span></i><span style="font-weight: 400;">), na makikita lamang sa mga hiwa-hiwalay na bahagi. Simple ang istrakturang vegetasyon (</span><i><span style="font-weight: 400;">vegetation structure</span></i><span style="font-weight: 400;">) na may kaunting layers at kalat-kalat sa kahabaan ng ilog.</span></p><p> </p><p><span style="font-weight: 400;">Nag-iiba din ang mga uri ng species (</span><i><span style="font-weight: 400;">species diversity</span></i><span style="font-weight: 400;">) sa bawat lugar, depende sa lokal na kondisyon tulad ng katatagan ng lupa (</span><i><span style="font-weight: 400;">soil stability</span></i><span style="font-weight: 400;">), kapal ng halaman (</span><i><span style="font-weight: 400;">vegetation cover</span></i><span style="font-weight: 400;">) at lapit sa ilog. Ayon kay Dr. Replan, kapansin-pansin ang natuklasan niya na “May ilang species ng halaman na lubos na naaangkop sa paulit-ulit na pagbaha at mabuway na lupa, habang ang ilan naman ay lumalago sa mga lugar na malayo sa direktang impluwensya ng ilog. Ipinapakita ng spatial variation na ito kung paano kasensitibo at kaspesyalisado ang mga riparian ecosystems.”</span></p><p> </p><p><span style="font-weight: 400;">Pinapakita rin ng kanilang pagsusuri kung gaano kalaki ang impluwensiya ng lokal na kapaligiran sa paghubog ng riparian ecosystems. Ang Amnay River ay isang malinaw na halimbawa kung paano nakakabuo ng </span><i><span style="font-weight: 400;">complex</span></i><span style="font-weight: 400;"> at </span><i><span style="font-weight: 400;">uneven plant communities</span></i><span style="font-weight: 400;"> ang isang sediment-influenced na tropikal na ilog. Nagpapatibay ito sa pangangailangan ng pamamahalang ekolohikal na naaangkop sa lugar, at pagkakaroon ng matibay na baseline data na magiging gabay sa konserbasyon at rehabilitasyon.</span></p><p> </p><p><span style="font-weight: 400;">“Kung may mga pagbabago dahil sa </span><i><span style="font-weight: 400;">natural disturbances</span></i><span style="font-weight: 400;"> or gawa ng mga aktibidad ng tao, may batayang magagamit ang mga susunod na mananaliksik at mga tagapagpatupad ng polisiya. Kaya ding magsilbing gabay ang impormasyon para sa mga proyektong rehabilitasyon dahil natukoy ang mga </span><i><span style="font-weight: 400;">native species</span></i><span style="font-weight: 400;"> na angkop na angkop sa lokal na kondisyon ng ilog, bagay na esensyal para sa mabisang rehabilitasyon at konserbasyon ng saribuhay,” pagtatapos ni Dr. Replan.</span></p><p> </p><p><span style="font-weight: 400;">Ang pag-aaral na “Floristic Diversity of Riparian and Associated Vegetation Along the Amnay River (The Philippines),” ay nalathala sa </span><i><span style="font-weight: 400;">Plant-Environment Interactions</span></i><span style="font-weight: 400;">.</span></p><p> </p><p><b>References:</b></p><p><span style="font-weight: 400;">Replan, E. L. (2026). Floristic diversity of riparian and associated vegetation along the Amnay river (The Philippines). </span><i><span style="font-weight: 400;">Plant-Environment Interactions</span></i><span style="font-weight: 400;">, </span><i><span style="font-weight: 400;">7</span></i><span style="font-weight: 400;">(1). </span><a href="https://doi.org/10.1002/pei3.70122"><span style="font-weight: 400;">https://doi.org/10.1002/pei3.70122</span></a></p>					</div>
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					</div><p>The post <a href="https://science.upd.edu.ph/halaman-sa-tabing-ilog-mahalaga-para-sa-konserbasyon%ef%bf%bc/">Halaman sa Tabing-Ilog: Mahalaga para sa Konserbasyon￼</a> first appeared on <a href="https://science.upd.edu.ph">SCIENCE - University of the Philippines Diliman</a>.</p>]]></content:encoded>
					
		
		
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