UP Geologists Report Subsidence Rates in Select PH Metropolitan Cities

UP Geologists Report Subsidence Rates in Select PH Metropolitan Cities

Published: December 05, 2024
By: Eunice Jean C. Patron

Land subsidence, or the gradual sinking of the ground, threatens not only Metro Manila but also other cities.

 

Extreme damage running along the length of a road in Marilao, Bulacan is visible. (Photo credit: Sulapas et. al., 2024)

Excessive groundwater extraction, rapid urbanization, tectonic motion, and the natural compaction of sediments contribute to land subsidence worldwide. This issue is worsened by rising sea levels due to climate change, leading to frequent and severe flooding especially during high tides or typhoons, as well as local contexts of hazard management regulations.

 

Jolly Joyce Sulapas, Audrei Anne Ybañez, and Dr. Alfredo Mahar Francisco Lagmay of the University of the Philippines – Diliman College of Science (UPD-CS), along with Kayla Milcah Marasigan and Julian Marie Bernice Grageda of the UP Resilience Institute Nationwide Operational Assessment of Hazards (UPRI-NOAH) analyzed land subsidence in major Philippine cities from 2014 to 2020.

 

Their land subsidence analysis showed that Bulacan, which is located in Greater Manila, has the highest sinking rate at 109 millimeters (mm) per year. This was also the first study to examine land subsidence in other cities, with rates of 11 mm per year in Metro Cebu, 38 mm per year in Metro Davao, 9 mm per year in Metro Iloilo, and 29 mm per year in Legazpi City. “The high population density of cities makes the information more relevant to the public, as its impact on people is greater,” Sulapas said. “Cities are also more vulnerable to land subsidence because the subsurface strata, or the rocks beneath the cities, are relatively younger.”

 

These sinking areas are mostly found in industrial and commercial zones, where large and expansive man-made structures intensify subsidence. Monitoring these areas is crucial, as subsidence increases flood risks, damages buildings and infrastructure, and causes economic losses. This hazard also increases the vulnerability of residents in coastal communities to high tides and storm surges aggravated by climate change.

 

“It seems like industrial complexes require a lot of water to keep their operations running. The same can be said for residential areas,” Sulapas noted.

 

A reconnaissance fieldwork near the trace of the West Valley Fault showing cracks on the road with vertical displacements of 5-7 cm and an aperture of 12 cm (Photo credit: Sulapas et. al., 2024)

The study recommends sustainable groundwater use and improved water management practices. Sulapas mentioned that previous studies on land subsidence were recognized by the National Water Resources Board (NWRB). “The Board then identified zones where groundwater usage would be restricted,” she said.

 

“My co-authors were part of a previous study on subsidence in Metro Manila and surrounding provinces. This was during the year 2010,” Sulapas added. “So more than a decade later, what we wanted to do is to update the deformation data. In the case of the Greater Manila area, what happened after more than a decade?”

 

Moving forward, the team of researchers plans to incorporate additional data, such as groundwater extraction in the major Philippine metropolitan cities covered in their study, and correlate it with existing information. They also intend to continuously update their data to include the years 2021 to the present, collaborating with other researchers interested in contributing to the study over the next decade and beyond.

 

The research, titled “Ground subsidence in major Philippine metropolitan cities from 2014 to 2020,” was published in the International Journal of Applied Earth Observation and Geoinformation, which publishes original papers that apply earth observation data to the inventory and management of natural resources and the environment.

 


For interview requests and other concerns, please contact media@science.upd.edu.ph.

 

References:

Sulapas, J. J., Ybañez, A. A., Marasigan, K. M., Grageda, J. M., & Lagmay, A. M. (2024). Ground subsidence in major Philippine metropolitan cities from 2014 to 2020. International Journal of Applied Earth Observation and Geoinformation. https://doi.org/10.2139/ssrn.4779261

CS Researchers Receive UPD 2024 REPS Chair and REPS Awards

CS Researchers Receive UPD 2024 REPS Chair and REPS Awards

Published: December 04, 2024
By: Eunice Jean C. Patron

Researchers from the University of the Philippines – Diliman College of Science (UPD-CS) are recipients of the University’s first-ever recognition for its Research, Extension, and Professional Staff (REPS).

 

Researchers from UPD-CS will be recognized at UP Diliman’s first-ever recognition focused on its Research, Extension, and Professional Staff (REPS).

The UP Diliman REPS Chair and REPS Awards aims to recognize the achievements of the REPS in the fields of research and creative work, extension services, and professional public service. These awards also aim to encourage REPS to advance knowledge and learning in their respective fields, establish scientific and thought laboratories, and develop collaborative programs that support UP’s mandate as the nation’s leading research university.

 

Three researchers from the UPD-CS Natural Sciences Research Institute (NSRI) earned the REPS Chair Awards. Meanwhile, one researcher each from NSRI, UPD-CS Marine Science Institute (MSI) and the UPD-CS National Institute of Physics (NIP), along with two from the UPD-CS Institute of Biology (IB), received the REPS Awards.

 

REPS Chair Awards Recipients

 

Dr. Charita S. Kwan is the head of NSRI’s Research and Analytical Services Laboratory. She has over 20 years of experience in projects related to environmental and analytical chemistry, with a focus on the distribution, fate, and transport of organic micropollutants.

 

Dr. Pierangeli G. Vital is the head of NSRI’s Biological Research and Services Laboratory. She has over a decade of experience in research and teaching within the field of environmental microbiology and food safety, publishing multiple articles in international peer-reviewed journals and papers.

 

Dr. Maria Corazon A. De Ungria is the head of NSRI’s DNA Analysis Laboratory. Her research focuses on human genetic diversity and leveraging DNA as a tool for human identification in criminal investigations, prosecuting sexual offenders and preventing wrongful convictions.


REPS Awards Recipients

 

Mary Ann Cielo R. San Diego is a registered microbiologist of NSRI’s Microbiological Research and Services Laboratory. Her research centers on wastewater microbiology, specifically the community and functional profiling of microorganisms in wastewater treatment plants.

 

John Michael L. Lastimoso is an Assistant Herbarium Curator of the Gregorio T. Velasquez Phycological Herbarium and a member of the Marine Phycology Laboratory at MSI, where he conducts biodiversity and systematics research on Indo-West Pacific macroalgae.

 

Dr. Hannah R. Bardolaza assists with the operation and maintenance of equipment in NIP’s Femtosecond Laser Laboratory. Her research focuses on materials science, specifically materials and devices for terahertz science and technology applications.

 

Melizar V. Duya is a university researcher in IB’s Biodiversity Research Laboratory. She has authored and co-authored publications on Philippine wildlife, including new species descriptions, and contributed to developing and identifying Key Biodiversity Areas in the country.

 

Mae Ashley G. Nacario is a university researcher in IB’s Pathogen-Host-Environment Interactions Research Laboratory. Her focus is on Environmental Microbiology, with a specialization in Microbial Source Tracking. She has already published 7 manuscripts in various Scopus-indexed journals.


Harriet Jane R. Caleja-Ballesteros is the sole staff member of IC’s Nuclear Magnetic Resonance (NMR) Facility.  Since 2019, she has managed to run around 3000 NMR samples for clients while doing research projects, mainly on quantitative NMR spectroscopy.


Joel I. Ballesteros is one of the three REPS of IC’s Analytical Services Laboratory (ASL). He got his BS and MS degrees from the same Institute and is currently finishing his dissertation on spectroscopy and chemometrics while working as a full-time university research associate.


The REPS Chair and REPS Awards ceremony will be held on Tuesday, December 10, 2024, at 9:00 AM, at the GT Toyota Auditorium, Asian Center, as part of the REPS Colloquium and General Assembly program. The recipients will be awarded with a plaque of recognition and a cash prize.

 

For interview requests and other concerns, please contact media@science.upd.edu.ph.

UP Geologists Lead the 2024 PRC Licensure Exam

UP Geologists Lead the 2024 PRC Licensure Exam

Published: November 27, 2024
By: Eunice Jean C. Patron

Six graduates of the University of the Philippines Diliman – College of Science’s National Institute of Geological Sciences (UPD-CS NIGS) secured spots in the top 10 of the Philippine Regulation Commission’s (PRC) annual Geologists Licensure Examination.

 

All 50 examinees from UPD-CS NIGS also passed the licensure exam, earning UPD the title of top-performing school with a 100% passing rate. Nationwide, 236 out of a total of 349 examinees successfully passed the examination, with a passing rate of 67.62%.

 

The annual PRC Geologists Licensure Examination was conducted online as a computer-based test from November 20 to 22, 2024.

 

It has also been nine years since UPD-CS NIGS last achieved a 100% passing rate in the PRC Geologists Licensure Examination in February 2016.

 

For interview requests and other concerns, please contact media@science.upd.edu.ph.

Two UPD-CS Professors Win 2024 NSTW Research and Development Award

Two UPD-CS Professors Win NSTW Research and Development Award

Published: November 26, 2024
By: Eunice Jean C. Patron

Dr. Pia Bagamasbad (left) and Dr. Aurelio de los Reyes V (right) will receive the 2024 NSTW Outstanding Research and Development Award for Basic Research.

Two scientists from the University of the Philippines – Diliman College of Science (UPD-CS) have been honored with the 2024 NSTW (National Science and Technology Week) Outstanding Research and Development Award for Basic Research by the National Academy of Science and Technology Philippines (NAST PHL).

 

Dr. Pia Bagamasbad of the UPD-CS National Institute of Molecular Biology and Biotechnology (UPD-CS NIMBB) and Dr. Aurelio de los Reyes V of the UPD-CS Institute of Mathematics (UPD-CS IM) were commended for their exceptional contributions to Philippine society through their research.

 

NAST PHL recognized Dr. Bagamasbad for her research on the connection between stress, altered light-dark cycles, and breast cancer. Her study identified KLF9 as a gene connecting cortisol and circadian rhythm disruptions to breast cancer risk and progression. “The knowledge that is generated from basic research provides the solid foundation that enables us to answer many practical problems,” said Dr. Bagamasbad, noting that many Nobel Prize Laureates in Physiology or Medicine were recognized for understanding molecular and cellular processes without immediate practical aims.

 

The Academy also acknowledged Dr. de los Reyes for his groundbreaking research on hormone-based contraceptives, awarding him the outstanding research prize. “Our research on contraception dosing strategies goes beyond controlling population growth. It’s about empowering women by giving them safer, more informed ways to decide when to conceive and start motherhood. This is about supporting their health, their choices, and their futures,” he shared. “Using mathematics, we aim to design strategies that not only improve medical outcomes but also ensure that these decisions can be made confidently and with better understanding.”

 

NAST PHL, mandated with recognizing outstanding contributions to science and technology by Filipino scientists across all fields, honors individuals and institutions that have made significant advancements in knowledge generation, research, and the promotion of science and technology in the Philippines.

 

Dr. Bagamasbad and Dr. de los Reyes will be awarded the Eduardo A. Quisumbing Medal for basic research, along with a plaque and cash prize, during the opening ceremony of NSTW on November 27. They are also invited to present their research at the ScienTeach: Symposium for the Youth on November 28.

 

Both scientists will be featured in #PilipiNAST Kapehan, a series of discussions between NAST PHL and media and science communicators designed to highlight the Academy’s programs, activities, awardees, members, and relevant national issues.

 

For interview requests and other concerns, please contact media@science.upd.edu.ph.

UPD-CS Launches Awareness Campaign on Genetic Modification and Gene Editing Research

UPD-CS Launches Awareness Campaign on Genetic Modification and Gene Editing Research

Published: November 14, 2024
By: Eunice Jean C. Patron

#GeneTalks aims to enhance understanding of genetic research while also addressing common misconceptions in the field. (Photo credit: UPD-CS Science Communication Team)

The University of the Philippines – Diliman College of Science (UPD-CS) recently organized a campaign focused on Genetic Modification (GM) and Gene Editing (GE) research in the country, as well as on the challenges faced by its researchers.

 

Titled “#GeneTalks,” the two-part, multi-stakeholder awareness campaign, spearheaded by the UPD-CS Office of the Associate Dean for Research, Innovation, Development, and Enterprise (OADRIDE), aims to foster understanding and elevate the level of public discourse on genetic research by discussing the challenges, opportunities, and potentials of research in GE and GM, while also addressing common misconceptions related to the field. This event series emerged in response to the Court of Appeals’ ruling, case no. CA-G.R. SP No. 00038, which restricts the use, testing, and importation of Genetically Modified Organisms (GMOs), and its potential impact on the academe’s role as a research institution.

 

The first forum held on November 4 and titled “Lab to Field,” explores GM research, its regulatory processes in the Philippines, and its importance in agriculture. The panel of esteemed speakers includes Dr. Ernelea Cao, Professor Emeritus at the UPD-CS Institute of Biology on regulatory processes for GM research and its significance; Atty. Edmund Jason Baranda, Managing Partner of Baranda and Associates, on the Court of Appeal’s ruling on GMOs; and Dr. Lourdes Taylo, Bt Eggplant Project Leader, on Bt eggplant and the role of GMOs in food security and nutrition.

 

“Understanding these dynamics is crucial for ensuring the ethical and responsible conduct of research, and for expanding our insights into GM research for the benefit of scientists, policymakers, and stakeholders,” said  UPD-CS National Institute of Molecular Biology and Biotechnology (UPD-CS NIMBB) Director Dr. Pia Bagamasbad during the forum, who observed that scientists may not be aware of the broader implications of GM research and products.

 

On the other hand, the second forum, held on November 11 and titled “Edit to Innovation,” covers GE technologies, their potential across various fields, and their broader implications. The panel of esteemed speakers includes Dr. Reynante Ordonio, Senior Science Specialist at the Philippine Rice Research Institute, on the current status of biotechnology in the Philippines and GE applications; and Dr. Ron Leonard Dy, Associate Professor at the NIMBB, on the use of GE in molecular diagnostics.

 

“Communicating genetic research through talks such as #GeneTalks provides transparency, allowing the public to ask questions and check the validity of the scientists’ claims. It is a way to bring about societal trust and acceptance.” shared Dr. Ma. Anita Bautista, NIMBB Deputy Director for Research and Extension and Member of the UPD-CS Technical Working Group for GMO-related concerns. “When scientists share information about genetic research and their outcomes, they implicate their authenticity, accountability, and moral and social values.”

 

Participants share their ideas during the mentoring sessions for feedback. (Photo credit: SPS)

For interview requests and other concerns, please contact media@science.upd.edu.ph.

Save Philippine Seas and UP Diliman College of Science Host 2-Day Workshop on Science Communication

Save Philippine Seas and UP Diliman College of Science Host 2-Day Workshop on Science Communication

Published: November 11, 2024
By: Eunice Jean C. Patron

Participants and organizers take a photo in front of the UPD-CS Admin Building. (Photo credit: SPS)

Selected students and researchers from the University of the Philippines – Diliman (UPD) participated in the Commservation Workshop, a two-day event focused on the basics of science communication and conservation. The workshop was organized by the UPD College of Science (UPD-CS) in collaboration with the non-profit organization Save Philippine Seas (SPS) and took place on October 12 and 14.

 

The Commservation Workshop is designed to build the science communication skills of conservation practitioners and enthusiasts, fostering a community of communicators for conservation. The workshop was open to UPD constituents interested in the conservation and restoration of the Philippines’ natural resources and environment, as well as in science communication.

 

A total of 21 participants were selected to join the workshop, and were introduced to the fundamentals of science communication, as well as data visualization, public speaking, grant writing, and fundraising. The activities allowed them to apply what they learned to their conservation efforts.

 

Apart from talks by invited speakers, the Commservation Workshop also included slam book sessions where participants could discuss their conservation efforts and aspirations in detail, as well as interactive mentorship sessions where they presented their communication outputs based on what they learned to the UPD-CS and SPS team for feedback and suggestions.

 

Participants share their ideas during the mentoring sessions for feedback. (Photo credit: SPS)

Participants expressed how the topics discussed during the workshop were beneficial to their initiatives, as well as helped them gain new knowledge and skills. “The Commservation workshop was a real eye-opener for me on the impact of science communication. It emphasized that research is more than just generating knowledge—it’s about making that knowledge accessible and relevant to a wider audience. It reminded me that the best science is the kind that reaches and resonates with people,” shared Kloudene Salazar, one of the participants of the workshop.

 

“As an alumna of UP who took classes under UPD-CS, I know how sessions like these and the networks we build can be transformative for the paths we want to pursue,” said Anna Oposa, Executive Director and Chief Mermaid of SPS. “Science communication is an essential skill for scientists, whether professional or aspiring. By communicating our research outputs and findings to a broader audience like policymakers and communities, we have the potential for greater impact.”

 

The Commservation Workshop invited esteemed speakers to expand participants’ knowledge of science communication. Dr. Inez Ponce De Leon, Associate Professor at the Department of Communication in Ateneo de Manila University, and freelance science communicator Christopher Ng introduced the concept of science communication; Cham Mamador, Data Visualization Specialist at Canva Philippines, discussed data visualization; and Oposa covered public speaking and grant writing.

 

For interview requests and other concerns, please contact media@science.upd.edu.ph.

Documentary on UP Marine Science Institute’s work on Plastics wins at Bantog Awards

Documentary on UP Marine Science Institute’s work on Plastics wins at Bantog Awards

Published: October 15, 2024

By: Eunice Jean C. Patron

MSI researchers are collecting sediment samples from coastal areas, which will be analyzed in their laboratory to detect the presence of microplastic particles. (Photo credit: Microbial Oceanography Laboratory)

A documentary featuring projects of the University of the Philippines – Diliman College of Science’s Marine Science Institute (UPD-CS MSI) received the Best Science and Technology Investigative Story (Audio-Visual) trophy at the Department of Science and Technology’s 2024 Bantog Awards for Science Communication.

 

Produced by the GMA Integrated News Digital Innovation and Strategic Lab for their DigiDokyu segment, the episode, “Ang Plastic Mo! The Philippine Plastic Problem,” delved into the effects of plastic on the country’s marine environment, the livelihoods of fisherfolk, and the food supply.

 

According to the World Bank, as cited in the documentary, the Philippines produces 2.7 million metric tons of plastic annually, 20% of which ends up in the ocean. Published research on plastics frequently mentions the Philippines as a top contributor to marine plastic pollution, yet most of this research is based on model projections and lacks actual baseline data collected from Philippine marine areas. The growing problem of plastics in the country and the lack of accurate data on plastics pushed MSI to create projects addressing plastic pollution.

 

PlastiCount Pilipinas

PlastiCount Pilipinas aims to raise awareness among Filipinos about the widespread presence of plastics, particularly in marine environments and coastal communities, by quantifying plastic pollution in the Philippines, thereby encouraging action to address the issue. The Institute’s innovative project utilizes advanced technologies, such as artificial intelligence (AI), to efficiently count and collect comprehensive and reliable information on plastics in Philippine waters, and to effectively visualize and understand their composition in local communities. Quantifying mismanaged plastics allows the Philippines to establish metrics to track increases or decreases in plastic waste. Identifying plastic debris in the country’s waters can also help in developing policies and solutions tailored to the types of plastic found in specific locations.

 

Circular Explorer Project

In partnership with the cement manufacturing company Holcim and the environmental organization One Earth One Ocean, MSI launched the Circular Explorer Project to empower students and communities to practice environmental sustainability through a science-driven approach to ocean research. The Circular Explorer is the first solar-powered sea vessel designed to collect plastic waste from the water for recycling and is capable of clearing up to four tons of plastic daily with its built-in sensors and plastic collectors.

 

PlasMics Project

MSI also oversees the DOST-funded Plastics in the Marine Environment, Trophic System, and Aquaculture in the Philippines (PlasMics) Project, which aims to determine the prevalence and potential impact of plastics on the marine environment, as well as their implications for biodiversity and aquaculture.

 

Dr. Deo Florence Onda, principal investigator of the Microbial Oceanography Laboratory (MOLab) responsible for these projects, shared that MSI is now working with agencies such as the Department of Environment and Natural Resources to harmonize the projects’ methodologies for national baselining. “The technology we are developing is already being adopted by national government agencies. That’s what we want – the university develops technology, and the national government adopts it for roll-out, application, and institutionalization.” MOLab also aims to make its initiatives more accessible to the general public through collaborations with media organizations.

 

DOST’s Bantog Awards for Science Communication aims to expand public interest in science, technology, and innovation, as well as to enhance science literacy in the Philippines. This year’s theme is “Driving Developments through Science Communication.”

 

For interview requests and other concerns, please contact media@science.upd.edu.ph.

UP Mathematicians Introduce a Different Approach in Detecting Potential Stock Market Crashes

UP Mathematicians Introduce a Different Approach in Detecting Potential Stock Market Crashes

Published: October 8, 2024

By: Harvey L. Sapigao

The process of Topological Data Analysis. (Photo credit: Riñon et. al. 2024)

A data analysis method that borrows concepts from topology – the so-called “rubber-sheet geometry” – may soon find its way to a stock trader’s toolkit in analyzing market movements. This method, called Topological Data Analysis (TDA), uncovers patterns in large datasets, preparing them for deeper analysis.

 

In a study published in the Philippine Journal of Science, Ela Mae Riñon and Dr. Rachelle Sambayan of the UP Diliman College of Science Institute of Mathematics (UPD-CS IM) demonstrated that TDA can be used as an early warning signal for stock market crashes. Their study, which analyzed stock data of three Philippine companies from 2019 to 2021, successfully anticipated periods when the market was about to crash.

 

“The findings suggest that [TDA] can help identify industries most affected during economic downturns, such as the COVID-19 pandemic, aiding investors and policymakers in minimizing risks,” they said.

 

The T in Topological Data Analysis

 

To understand TDA, it may be helpful to compare it with how we observe stars. At first glance, the night sky appears as a seemingly random plot of stars scattered across the vast canvas of the universe. However, with extended observation, patterns emerge: clusters of stars, constellations, and voids become apparent the moment we recognize them. As we continue to gaze at the sky, the random stars fade into the background, while the clusters, constellations, and voids take the spotlight.

 

This effect is similar to what TDA does with large sets of data points. Essentially, TDA reveals hidden geometric structures within datasets, allowing insights to be drawn from what previously looked like an ambiguous clump of points. “TDA helps uncover patterns, such as clusters forming constellations, loops, or voids,” said the authors.

 

One tool in TDA, called persistent homology, follows a series of steps to systematically uncover patterns. First, researchers draw a small ball around the data points. Next, they gradually expand the balls until some of them overlap. When this happens, they connect the corresponding points. The balls continue to expand until the points form various figures, which are then classified into what are called homology groups.

 

Researchers classify the figures into three homology groups: connected components, which are open shapes like line segments; loops, which are closed shapes like triangles; and cavities, which are shapes that extend to the third dimension. As the balls expand, the figures can change from one homology group to another. A connected component, for example, might attach to a data point that closes it off, transforming it into a loop.

As the balls expand, the points connect, forming different homology groups. (Photo credit: Riñon et. al. 2024)

Throughout this process, researchers observe how quickly the figures change homology groups. Figures that switch groups over a short range of ball sizes are considered noise, while those that persist for wider ranges are deemed more significant. Eventually, when the balls are large enough, they will all overlap and all points will be connected into one big structure, marking the end of the process.

 

Which figures quickly change and which persist is the core idea of TDA, revealing key features of the data. Moreover, the authors explained that “unlike standard methods, TDA is robust to noise and can detect complex patterns that might otherwise go unnoticed, offering a deeper understanding of high-dimensional data.”

 

Putting TDA to the Test

 

Dr. Sambayan and Riñon applied TDA to the stock price data of three Philippine companies – Cebu Air (CEB), PAL Holdings (PAL), and Century Pacific Food (CNPF) – from January 2019 to January 2021. They found that when the market was about to crash, the data points began to cluster together, which made their corresponding figures more likely to change homology groups. In other words, the persistence of homology groups weakens as the stock prices start to plummet.

 

“This weakening of persistence is unexpected because it reveals a distinct change in the data’s topological structure during market downturns, which contrasts with the scattered point clouds observed during stable periods,” the authors explained.

 

To track these changes, they used a persistence landscape, a chart that maps out the crash probability of a stock. In 2019, during a period when CEB was about to crash, its persistence landscape spiked, indicating a high crash probability of 40-60%. Similarly, in early 2020, the landscape showed a high crash probability prior to another CEB crash, which was attributed to pandemic travel bans and lockdowns.

 

Their study also revealed that TDA is indeed robust to noise, which refers to ordinary fluctuations within the data. Stock prices naturally fluctuate, but not every dip signals an impending crash. Unlike CEB, both PAL and CNPF were more stable during the onset of the pandemic. Although they experienced minor dips during this period, they did not experience a significant crash, which the model correctly anticipated.

 

However, the authors noted that they only applied the analysis to three companies over a brief period and that other markets or time frames might yield different results. “Additionally, the study’s approach to determining thresholds and window sizes may need further refinement to ensure consistency and accuracy in different contexts,” they said.

 

To further test TDA, the authors recommend extending the analysis to other markets and time frames. “Another avenue for future research is applying the TDA approach to other types of time series data, such as exchange rates, to explore its effectiveness in detecting structural changes and understanding the behavior of stock prices and other financial indicators under different economic conditions,” they concluded.

 

For interview requests and other concerns, please contact media@science.upd.edu.ph.

 

References:

Riñon E.M, and Sambayan R. (June 2024). Topological Approach for Detection of Structural Breakpoints in Philippine Stock Price Data Surrounding the COVID-19 Pandemic. Philippine Journal of Science, 153(3): 1177–1188. https://philjournalsci.dost.gov.ph/129-vol-153-no-3-june-2024/2118-topological-approach-for-detection-of-structural-breakpoints-in-philippine-stock-price-data-surrounding-the-covid-19-pandemic

 

UP Scientists Create Thermoresponsive Polymers for Potential Biomedical Use

UP Scientists Create Thermoresponsive Polymers for Potential Biomedical Use

Published: October 4, 2024

By: Eunice Jean C. Patron

Thermoresponsive polymers are molecules that undergo significant changes in their properties in response to temperature changes and are widely used in biomedicine, such as drug delivery, tissue growth, and gene transfer, as noted by researchers Ward and Georgiou in their 2011 study.

 

One example of a thermoresponsive polymer is poly(N-isopropylacrylamide), which is used to deliver drugs, such as calcitonin and insulin, to their target organ. According to scientist Dirk Schmaljohann, poly(N-isopropylacrylamide) keeps the drug intact as it passes through the stomach, and once it reaches the intestines, which have a different pH level, the polymer breaks down and releases the drug.

 

While there are already existing conventional methods to synthesize polymers, it is difficult to control how monomers—small molecules that make up polymers—connect. This leads to varying polymer chain lengths, which affect the performance of the polymers. This prompted chemists from the University of the Philippines – Diliman College of Science (UPD-CS) to identify a simple, inexpensive, and environmentally friendly approach of creating thermoresponsive polymers.

Synthesis of two different architectures of copolymers of MMA and DEGMEMA using RAFT polymerization in [HPY][PF6].

(Photo credit: Madrid et al., 2024)

Using the Reversible Addition Fragmentation Chain Transfer (RAFT) polymerization, Ludhovik Luiz Madrid and Dr. Susan Arco from the UPD-CS Institute of Chemistry (UPD-CS IC), along with Ser John Lynon Perez of the UPD-CS Natural Sciences Research Institute (UPD-CS NSRI), successfully created thermoresponsive polymers using two monomers—di(ethylene glycol) methyl ether methacrylate (DEGMEMA) and methyl methacrylate (MMA)—in  a hexylpyridinium ionic liquid, N-hexylpyridinium hexafluorophosphate ([HPY][PF6]). Both linear and hyperbranched structures were successfully synthesized, using ethylene glycol dimethacrylate (EGDMA) as the crosslinking agent for the hyperbranched copolymer. The polymers produced by the researchers were biocompatible, meaning they can interact with living body tissues without causing adverse reactions.

 

“RAFT polymerization helps control the growth of polymer chains by mitigating the formation of chains that can no longer grow (a.k.a. ‘dead’ polymers), thereby creating a narrower molecular weight distribution  which can allow more tailored polymer designs or properties,” Madrid explained. Solvents used in RAFT polymerization are also typically organic and volatile, posing environmental and health risks. To lessen these risks, the researchers used [HPY][PF6], a type of ionic liquid that has better polymerization kinetics and is less harmful to the environment.

 

Apart from demonstrating the effectiveness of synthesizing polymers with [HPY][PF6] through RAFT polymerization, the study introduced new possibilities in polymer research. “The results open up the potential for using other hexylpyridinium ionic liquids to create dual-responsive polymers (e.g. responsive to both temperature and pH), which are valuable for biomedical applications such as drug delivery,” Madrid concluded.

 

For interview requests and other concerns, please contact media@science.upd.edu.ph.

 

References:

 

Madrid, L. L., Perez, S. J., & Arco, S. (2024). RAFT copolymerization of methyl methacrylate and di(ethylene glycol) methyl Ether methacrylate in a hexylpyridinium Ionic liquid. Journal of the Chinese Chemical Society. https://doi.org/10.1002/jccs.202400197

 

Schmaljohann, D. (2006). Thermo- and pH-responsive polymers in drug delivery. Advanced Drug Delivery Reviews, 58(15), 1655-1670. https://doi.org/10.1016/j.addr.2006.09.020

 

Ward, M. A., & Georgiou, T. K. (2011). Thermoresponsive polymers for biomedical applications. Polymers, 3(3), 1215-1242. https://doi.org/10.3390/polym3031215

Scientists Confirm Two Domesticated Buffalo Species in PH

Scientists Confirm Two Domesticated Buffalo Species in PH

Published: September 17, 2024

By: Eunice Jean C. Patron

Domesticated buffaloes (Bubalus bubalis) in the country have traditionally been classified into two subspecies: swamp buffaloes and riverine buffaloes. A recent study, however, provides evidence that these two are not subspecies, but are instead distinct from each other.

A Philippine native carabao (Bubalus kerabau Fitzinger, 1860) dam and her calf grazing in Pitogo Island, Bohol.

(Photo credit: Lilian P. Villamor, from Ruane et al., 2023)

Swamp buffaloes (Bubalus bubalis carabanensis) are primarily used to assist farmers with tilling the land, transporting tools, and, alternatively, for meat, milk, hide, and manure, which is used as organic fertilizer. Riverine buffaloes (Bubalus bubalis bubalis), on the other hand, are mainly used in milk production. In the Philippines, crossbreeding and backcrossing these two breeds on a large scale helps create animals with improved potential for milk and meat production, despite their differences. Hybridization of swamp and river buffaloes has limited success, sometimes producing viable offspring that don’t achieve the desired traits.

 

A team of researchers conducted an investigation to clarify the taxonomic designation of swamp and riverine buffaloes in the Philippines. They discovered that the DNA sequences of the genes from both swamp and riverine buffaloes are distinguishable and that their chromosome numbers are different, affirming that they are two distinct species, not just subspecies of Bubalus bubalis.

 

The research team is comprised of Dr. Ian Kendrich C. Fontanilla, Nelvie Fatima Jane A. Soliven, John Gregor A. Roño, Francis L. Fontanilla, Emerson R. Servo, and Dr. Ernelea P. Cao of the University of the Philippines – Diliman College of Science’s Institute of Biology (UPD-CS IB) and Dr. Lilian P. Villamor, Therese Patricka C. Cailipan, Alexander M. Paraguas, and Aivhie Jhoy E. Cuanang from the Department of Agriculture – Philippine Carabao Center (DA-PCC).

 

“These results corroborate the observed differences in their appearances. Swamp buffaloes can be identified by the white or light gray markings on their lower jaw and brisket, known as a chevron, as well as their lighter skin and coat color compared to riverine buffaloes. They are also smaller, weighing between 325 and 450 kg, and have crescent-shaped horns. They are mainly used as draught animals,” said Dr. Villamor, citing data from her previous studies on buffaloes. “River buffaloes, on the other hand, are larger, weighing between 450 and 1,000 kg, and have curly horns. They are primarily raised for milk and meat production.”

A riverine buffalo (Bubalus bubalis Linnaeus, 1758). (Photo credit: Therese Patricka C. Cailipan and Sonny C. Ramos)

According to the team, the Philippine native carabao, which is currently classified as Bubalus bubalis carabanensis, should be now considered as Bubalus kerabau Fitzinger, 1860. “The reclassification of the Bubalus bubalis carabanensis to Bubalus kerabau Fitzinger, 1860 supports earlier assumptions that riverine and swamp buffaloes are distinct,” added Dr. Fontanilla. “Confusions on the classifications of the two buffaloes have implications on the breeding program of these species.”

 

As their study was limited to examining the chromosomes of only swamp and riverine buffaloes, the researchers plan to include chromosomes from crossbred buffaloes in future studies to gain new insights into how these different types of buffaloes are genetically related and potentially improve the classification of the Bubalus bubalis.

 

The study, titled “Molecular Data and Karyotype Revealed Two Distinct Species of Domesticated Water Buffaloes in the Philippines,” offers valuable insights into the diversity of domesticated buffaloes, and can guide conservation and management efforts, particularly in developing potential hybrids with desired traits. It was published in the Philippine Journal of Science, an open-access, single-blind peer-reviewed journal on natural sciences, engineering, mathematics, and social sciences.

 

For interview requests and other concerns, please contact media@science.upd.edu.ph.

 

References:

 

Cailipan, T. P., Paraguas, A., Cuanang, A. J., Soliven, N. F., Roño, J. G., Fontanilla, F., Servo, E., Cao, E., Fontanilla, I. K., & Villamor, L. (2023). Molecular data and karyotype revealed two distinct species of domesticated water buffaloes in the Philippines. Philippine Journal of Science, 152(5). https://doi.org/10.56899/152.05.27

 

Cailipan, T.P.C., Villamor, L.P. 2021.  Molecular characterization of SRY gene in the Philippine Carabao (Bubalus bubalis) swamp buffalo populations. SciEnggJ 14(2):291-296.

 

Ruane, J., Mba, C., Boettcher, P., Koskela, J., Mair, G., & Ramasamy, S. (2023). Case studies of the use of agricultural biotechnologies to meet the needs of smallholders in developing countries. Food & Agriculture Org.

 

Villamor, L.P., Takahashi, Y., Nomura, K. and Amano T. 2021. Genetic diversity of Philippine Carabao (Bubalus bubalis) using mitochondrial DNA D-loop variation: implications to conservation and management. Philippine Journal of Science, 150(3): 837-846.